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CAS RN: 66852-54-8 | Product Number: H1457
Halobetasol Propionate
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Purity: >98.0%(HPLC)
Synonyms:
- 21-Chloro-6α,9α-difluoro-11β,17α-dihydroxy-16β-methyl-1,4-pregnadiene-3,20-dione 17-Propionate
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
NT$1,470
|
20 | 0 | It can be shipped in about 3-4 weeks after ordering | |
| 100MG |
NT$4,452
|
3 | 12 | It can be shipped in about 3-4 weeks after ordering |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | H1457 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__5H__3__1ClF__2O__5 = 484.96 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 25MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 66852-54-8 |
| Reaxys Registry Number | 11109992 |
| MDL Number | MFCD00866013 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Specific rotation [a]20/D | +89.0 to +93.0 deg(C=1, Dioxane) |
Properties (reference)
| Melting Point | 221 °C |
| Specific Rotation | 91° (C=1,Dioxane) |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | TU3723500 |
Transport Information:
| H.S.code* | 2937.22-000 |
Application
Halobetasol propionate: A Super-Potent Corticosteroid
Halobetasol propionate is a super-potent corticosteroid with additional fluorine at the 6α position when compared with clobetasol 17-propionate [C2612]. The additional fluorine in the 6α position further increases its topical anti-inflammatory and antiproliferative activities. In addition, an ointment formulation in combination of halobetasol propionate and fusidic acid [F1007] for treatment of dermal conditions have been reported. (The product is for research purpose only.)
References
- Halobetasol versus clobetasol: A study of potency
- A degradation product of halobetasol propionate-characterization and structure
- Formulation and evaluation of novel combined halobetasol propionate and fusidic acid ointment
- Spectrophotometric determination of clobetasol propionate, halobetasol propionate, quinagolide hydrochloride, through charge transfer complexation
- Screening for corticosteroids in topical pharmaceuticals by HPLC with a scanning ultraviolet detector
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