Maximum quantity allowed is 999
Please select the quantity
CAS RN: 1185167-55-8 | Product Number: I1057
2-Isopropyl-4-(N-methylaminomethyl)thiazole Dihydrochloride

Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
Product Number | I1057 |
Purity / Analysis Method ![]() |
>98.0%(T)(HPLC) |
Molecular Formula / Molecular Weight | C__8H__1__4N__2S·2HCl = 243.19 |
Physical State (20 deg.C) | Solid |
Storage Temperature ![]() |
Refrigerated (0-10°C) |
Condition to Avoid | Heat Sensitive |
Packaging and Container ![]() |
1G-Glass Bottle with Plastic Insert (View image) |
CAS RN | 1185167-55-8 |
PubChem Substance ID | 354334764 |
MDL Number | MFCD11841218 |
Specifications
Appearance | White to Light yellow to Light orange powder to crystal |
Purity(HPLC) | min. 98.0 area% |
Purity(Nonaqueous Titration) | min. 98.0 % |
NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
H.S.code* | 2934.10-000 |
Application
A Synthetic Intermediate of Cobicistat
This product is used for the synthesis of cobicistat which is a cytochrome P450 3A (CYP3A) inhibitor that can be used to enhance the pharmacokinetic profile of certain anti-HIV-1 agents.
References
- Process for the preparation of cobicistat and intermediates thereof
- L. R. Vadali, R. Konda, R. Dandala, WO/2015/083066
- Process for the preparation of 1,3-thiazol-5-ylmethyl[(2R,5R)-5-{[(2S)-2- [(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl] methyl}carbamoyl)amino]-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate (cobicistat)
- S. Thirumalai Rajan, S. Eswaraiah, G. Madhusudhan, K. Satyanarayana, J. Malleswara Reddy, WO/2016/132378.
- A process for preparation of cobicistat
- S. Simhadri, Y. Mohammad, A. R. Manda, V. S. K. Indukuri, S. R. Gorantla, C. S. Anjaneyulu, WO/2016/128885.
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.