Maximum quantity allowed is 999
Please select the quantity
CAS RN: 139298-40-1 | Product Number: K0055
KN-93
×
![]()
×
Purity: >98.0%(HPLC)
Synonyms:
- N-[2-[[[3-(4-Chlorophenyl)allyl](methyl)amino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5MG |
NT$5,124
|
27 | 0 | Contact Us | |
| 25MG |
NT$17,766
|
10 | 12 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | K0055 |
| Purity / Analysis Method | >98.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__2__6H__2__9ClN__2O__4S = 501.04 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 5MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 139298-40-1 |
| Reaxys Registry Number | 8357363 |
| PubChem Substance ID | 354335639 |
| MDL Number | MFCD00236424 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Elemental analysis(Nitrogen) | 5.00 to 6.00 % |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
| RTECS# | DB1576070 |
Transport Information:
| H.S.code* | 2935.90-000 |
Application
KN-93: A Potent and Specific Inhibitor of Ca2+/Calmodulin-Dependent Protein Kinase II (CaMKII)
KN-93 is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) which is a multifunctional serine/threonine kinase with numerous roles in human physiology. CaMKII mediates immediate effects due to phosphorylation of cellular proteins such as ion channels and calcium handling proteins.
References
- The newly synthesized selective calcium/calmodulin dependent protein kinase II inhibitor KN-93 reduces dopamine contents in PC12h cells
- Ca2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor
- NMDA receptor subunit composition controls synaptic plasticity by regulating binding to CaMKII
- Ca2+/calmodulin-dependent protein kinase modulates cardiac ryanodine receptor phosphorylation and sarcoplasmic reticulum Ca2+ leak in heart failure
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.