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CAS RN: 545-47-1 | Product Number: L0321
Lupeol
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Purity: >97.0%(HPLC)
Synonyms:
- 20(29)-Lupen-3β-ol
- 3β-Hydroxy-20(29)-lupene
- Fagarasterol
- Lup-20(29)-en-3β-ol
- (1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-Hexamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-ol
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 25MG |
NT$4,998
|
7 | 15 | Contact Us | |
| 100MG |
NT$14,700
|
8 | 0 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | L0321 |
Purity / Analysis Method 
|
>97.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__3__0H__5__0O = 426.73 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
100MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 545-47-1 |
| Reaxys Registry Number | 2063497 |
| PubChem Substance ID | 468592149 |
| Merck Index (14) | 5608 |
| MDL Number | MFCD00017351 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC)(CAD) | min. 97.0 area% |
| Specific rotation | +27.0 to +29.0 deg (C=0.5, CHCl3) |
| NMR | confirm to structure |
| Melting point | 208.0 to 212.0 °C |
Properties (reference)
| Melting Point | 210 °C |
| Maximum Absorption Wavelength | 350 nm (CHCl__3) |
| Solubility (soluble in) | Ether, Benzene |
GHS
Related Laws:
| RTECS# | OK5763000 |
Transport Information:
| H.S.code* | 2906.19-000 |
Application
Lupeol: an anti-inflammatory triterpen targeting key signaling pathways
Lupeol is a pentacyclic triterpen contained in vegetable oils, cereals, fruits and vegetables. It has been reported that lupeol has potent anti-inflammatory, anti-carcinogenic, anti-mutagenic, and anti-malarial activity.1) Many studies on the mechanisms of action suggest that lupeol is a multi-target agent with immense anti-inflammatory potential targeting key signaling pathways which involve nuclear factor kappa B (NF-κB), cFLIP, Fas, Kras, phosphatidylinositol-3-kinase (PI3K)/Akt and Wnt/β-catenin in a variety of cells.2-4) (The product is for research purpose only.)
References
- 1) Lupeol: Connotations for chemoprevention (a review)
- 2) Lupeol modulates NF-κB and PI3K/Akt pathways and inhibits skin cancer in CD-1 mice
- 3) Lupeol, a novel anti-inflammatory and anti-cancer dietary triterpene (a review)
- 4) Beneficial health effects of lupeol triterpene: A review of preclinical studies (a review)
- 5) Separation and identification of some common isomeric plant triterpenoids by thin-layer chromatography and high-performance liquid chromatography
Product Documents (Note: Some products will not have analytical charts available.)
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