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CAS RN: 119478-56-7 | Product Number: M2279
Meropenem Trihydrate
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Purity: >98.0%(T)(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
NT$4,368
|
≥40 | ≥100 | It can be shipped in about 3-4 weeks after ordering | |
| 5G |
NT$15,204
|
1 | ≥60 | It can be shipped in about 3-4 weeks after ordering |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | M2279 |
| Purity / Analysis Method | >98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__7H__2__5N__3O__5S·3H__2O = 437.51 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 119478-56-7 |
| Related CAS RN | 96036-03-2 |
| PubChem Substance ID | 135727273 |
| Merck Index (14) | 5900 |
| MDL Number | MFCD08600005 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Specific rotation [a]20/D | -17.0 to -21.0 deg(C=0.44, H2O) |
| Water | 11.4 to 13.4 % |
Properties (reference)
| Specific Rotation | -18° (C=0.44,H2O) |
| Solubility in water | Soluble |
GHS
Related Laws:
| RTECS# | CL5446507 |
Transport Information:
| H.S.code* | 2941.90-000 |
Application
Meropenem: A Carbapenem Antibiotic with Broad Spectrum of Activity and Stability to β-Lactamases
Meropenem, which is the second carbapenem antibiotic, has a broad spectrum of activity that includes activity against gram-positive bacteria and excellent gram-negative aerobic and anaerobic activity. It has enhanced gram-negative activity relative to imipenem (the first carbapenem antibiotic)-cilastatin and often retains activity against strains resistant to third-generation cephalosporins and imipenem-cilastatin. It has increased stability to β-lactamases compared with imipenem.
References
- Novel carbapenem-hydrolyzing β-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae
- Carbapenem activities against Pseudomonas aeruginosa: respective contributions of OprD and efflux systems
- T. Köhler, M. Michea-Hamzehpour, S. F. Epp, J.-C. Pechere, Antimicrob. Agents Chemother. 1999, 43, 424.
- Meropenem: a review of its antibacterial activity, pharmacokinetic properties and clinical efficacy
- Comparative review of the carbapenems
- Meropenem: a review of its use in the treatment of serious bacterial infections
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