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CAS RN: 4876-14-6 | Product Number: O0468
3-(2-Oxo-1,2-dihydro-4-quinolinyl)-DL-alanine Hydrochloride
									 
							Purity: >98.0%(HPLC)(N)
Synonyms:
						
						- 2-Amino-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic Acid Hydrochloride
 
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| Product Number | O0468 | 
Purity / Analysis Method  
                                     | 
                                    >98.0%(HPLC)(N) | 
| Molecular Formula / Molecular Weight | C__1__2H__1__2N__2O__3·HCl = 268.70 | 
| Physical State (20 deg.C) | Solid | 
Storage Temperature  
                                     | 
                                    Refrigerated (0-10°C) | 
| Store Under Inert Gas | Store under inert gas | 
| Condition to Avoid | Hygroscopic,Heat Sensitive | 
| CAS RN | 4876-14-6 | 
| Reaxys Registry Number | 5386599 | 
| PubChem Substance ID | 468592523 | 
| MDL Number | MFCD03839816  | 
                                
Specifications
		  | Appearance | White to Almost white powder to crystal | 
| Purity(HPLC) | min. 98.0 area% | 
| Purity(with Total Nitrogen) | min. 98.0 % | 
| Specific rotation [a]20/D | -1.0 to +1.0 deg(C=0.1, DMSO) | 
| NMR | confirm to structure | 
		Properties (reference)
	| Melting Point | 225 °C | 
 
						 GHS
						  
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						Transport Information:
							| H.S.code* | 2933.79-000 | 
			Application
		
			A Key Synthetic Intermediate of Rebamipide
		
		This product is a key synthetic intermediate of rebamipide [R0085] which is an anti-gastritis and anti-gastric ulcer agent.
References
- Studies on 2(1H)-Quinolinone Derivatives as Gastric Antiulcer Active Agents. 2-(4-Chlorobenzoylamino)-3-[2 (1H)-quinolinon-4-yl] propionic Acid and Related Compounds
 - Synthesis and antiulcer activity of optical isomers of 2-(4-chlorobenzoylamino)-3-[2(1H)-quinolinon-4-yl]propionic acid (rebamipide)
 
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