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CAS RN: 189028-93-1 | Product Number: P2111
(S)-4-Phenyl-3-[5-(4-fluorophenyl)-5-oxopentanoyl]-2-oxazolidinone
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![(S)-4-Phenyl-3-[5-(4-fluorophenyl)-5-oxopentanoyl]-2-oxazolidinone](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "(S)-4-Phenyl-3-[5-(4-fluorophenyl)-5-oxopentanoyl]-2-oxazolidinone")
Purity: >98.0%(HPLC)(N)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
NT$2,730
|
16 | 0 | It can be shipped in about 2 weeks after ordering | |
| 25G |
NT$10,542
|
21 | 0 | It can be shipped in about 2 weeks after ordering |
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* The storage conditions are subject to change without notice.
| Product Number | P2111 |
| Purity / Analysis Method | >98.0%(HPLC)(N) |
| Molecular Formula / Molecular Weight | C__2__0H__1__8FNO__4 = 355.37 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Room Temperature (Recommended in a cool and dark place, <15°C) |
| CAS RN | 189028-93-1 |
| Reaxys Registry Number | 9077797 |
| PubChem Substance ID | 253660310 |
| MDL Number | MFCD08061377 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(with Total Nitrogen) | min. 98.0 % |
| Melting point | 90.0 to 94.0 °C |
| Specific rotation [a]20/D | +49.0 to +54.0 deg(C=0.2, CHCL3) |
Properties (reference)
| Melting Point | 92 °C |
| Specific Rotation | 52° (C=0.2,CHCl3) |
| Solubility (soluble in) | Acetone |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2934.99-000 |
Application
An Intermediate in the Synthesis of Ezetimibe
This reagent is an intermediate in the synthesis of ezetimibe, which is a selective acyl-CoA: cholesterol acyltransferase (ACAT) inhibitor used in hypercholesterolemia.
References
- Process for preparing Ezetimibe intermediate by an acid enhanced chemo- and enantioselective CBS catalyzed ketone reduction
- Process for preparing Ezetimibe intermediate by enantioselective CBS catalyzed ketone reduction with BH3-DEA prepared in situ
- Burkholderia cenocepacia: a new biocatalyst for efficient bioreduction of ezetimibe intermediate
- Lipase catalyzed kinetic resolution for the production of (S)-3-[5-(4-fluoro-phenyl)-5-hydroxy-pentanoyl]-4-phenyloxazolidin-2-one: An intermediate for the synthesis of ezetimibe
PubMed Literature
Product Documents (Note: Some products will not have analytical charts available.)
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