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CAS RN: 135575-42-7 | Product Number: P2534
Pneumocandin B0
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Purity: >96.0%(HPLC)
Synonyms:
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
NT$4,368
|
10 | 29 | Contact Us | |
| 50MG |
NT$15,246
|
≥40 | 1 | Contact Us |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | P2534 |
Purity / Analysis Method 
|
>96.0%(HPLC) |
| Molecular Formula / Molecular Weight | C__5__0H__8__0N__8O__1__7 = 1,065.23 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (<0°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container
|
50MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 135575-42-7 |
| Reaxys Registry Number | 4902219 |
| PubChem Substance ID | 354335442 |
| MDL Number | MFCD28168025 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Elemental analysis(Nitrogen) | 9.50 to 11.50 % |
Properties (reference)
| Maximum Absorption Wavelength | 276 nm (MeOH) |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
Pneumocandin B0: A Naturally Occurring Lipophilic Cyclic Peptide with Antifungal Activity
Pneumocandin B0 is a naturally occurring lipophilic cyclic peptide isolated from the fungus, Glarea lozoyensis. It is a potent antifungal agent and acts by inhibiting the synthesis of β-(1,3)-D-glucan, an essential component of the cell wall of susceptible fungi. Pneumocandin B0 is also used as a starting molecule for some semisynthetic antifungal agents, such as caspofungin. (The product is for research purpose only.)
References
- Pneumocandins from Zalerion arboricola. I. Discovery and isolation
- Morphological effects of lipopeptides against Aspergillus fumigatus correlate with activities against (1,3)-β-D-glucan synthase
- Reclassification of a pneumocandin-producing anamorph, Glarea lozoyensis gen. et sp. nov., previously identified as Zalerion arboricola
- Synthesis of the Antifungal β-1,3-Glucan Synthase Inhibitor CANCIDAS (Caspofungin Acetate) from Pneumocandin B0
- Discovery and development of first in class antifungal caspofungin (CANCIDAS®)--a case study
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