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CAS RN: 64443-05-6 | Product Number: T2665
Tetrakis(acetonitrile)copper(I) Hexafluorophosphate
									 
							Purity: >97.0%(T)
Synonyms:
						
						Product Documents:
                    
				
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| Product Number | T2665 | 
Purity / Analysis Method  
                                     | 
                                    >97.0%(T) | 
| Molecular Formula / Molecular Weight | C__8H__1__2CuF__6N__4P = 372.72 | 
| Physical State (20 deg.C) | Solid | 
Storage Temperature  
                                     | 
                                    Frozen (<0°C) | 
| Store Under Inert Gas | Store under inert gas | 
| Condition to Avoid | Air Sensitive,Moisture Sensitive,Heat Sensitive | 
| CAS RN | 64443-05-6 | 
| Reaxys Registry Number | 14262634 | 
| PubChem Substance ID | 87561580 | 
| MDL Number | MFCD00064810  | 
                                
Specifications
		  | Appearance | White to Almost white powder to crystal | 
| Purity(Potassium permanganate method) | min. 97.0 % | 
| NMR | confirm to structure | 
		Properties (reference)
	| Melting Point | 160 °C(dec.) | 
 
						 GHS
						 | Pictogram | 
										   		 
								    			 | 
								   	 
| Signal Word | Warning | 
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation.  | 
                                
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention.  | 
                                
 
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							| H.S.code* | 2931.59-000 | 
			Application
		
			Perfluoroalkylation using Perfluoro Acid Anhydrides
		
		
Reference
- Perfluoroalkylation of Unactivated Alkenes with Acid Anhydrides as the Perfluoroalkyl Source
 
			Application
		
			Copper Catalyzed Asymmetric Conjugate Addition
		
		
References
- Catalytic Asymmetric Synthesis of Chiral Tertiary Organoboronic Esters through Conjugate Boration of β-Substituted Cyclic Enones
 - Searching for Practically Useful P-Chirogenic Phosphine Ligands
 
			Application
		
			Catalytic Asymmetric Vinylogous Conjugate Addition of Unsaturated Butyrolactones to α,β-Unsaturated Thioamides
		
		
Reference
			Application
		
			Copper-catalyzed C―H Amidation of Unactivated Arenes
		
		
Typical Procedure: 
To a stirred mixture of [Cu(CH3CN)4]PF6 (0.010 g, 0.026 mmol) and neocuproine (0.005 g, 0.024 mmol) in the arene (ca. 1 mL) is added N-tosyloxy-2,2,2-trichloroethylcarbamate (0.050 g, 0.138 mmol) and the mixture is allowed to stir at 140 °C for 8 h. The reaction mixture is cooled to room temperature, filtered through a pad of silica, washed with CH2Cl2, and the filtrate is concentrated under vacuum. The residue is purified by silica chromatography using 5–15% Et2O in hexanes to obtain the regioisomeric mixture of aminated arenes. The isomer ratio is determined by NMR using 1,3,5-trimethoxybenzene as a reference.
To a stirred mixture of [Cu(CH3CN)4]PF6 (0.010 g, 0.026 mmol) and neocuproine (0.005 g, 0.024 mmol) in the arene (ca. 1 mL) is added N-tosyloxy-2,2,2-trichloroethylcarbamate (0.050 g, 0.138 mmol) and the mixture is allowed to stir at 140 °C for 8 h. The reaction mixture is cooled to room temperature, filtered through a pad of silica, washed with CH2Cl2, and the filtrate is concentrated under vacuum. The residue is purified by silica chromatography using 5–15% Et2O in hexanes to obtain the regioisomeric mixture of aminated arenes. The isomer ratio is determined by NMR using 1,3,5-trimethoxybenzene as a reference.
References
			PubMed Literature
		Documents
Product Articles
  		        [Research Articles] Perfluoroalkylation using Perfluoro Acid Anhydrides[Research Articles] Catalytic Asymmetric Vinylogous Conjugate Addition of Unsaturated Butyrolactones to α,β-Unsaturated Thioamides
[Research Articles] Copper-catalyzed C—H Amidation of Unactivated Arenes
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