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CAS RN: 491-67-8 | Product Number: T2721
Baicalein
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Purity: >98.0%(T)
Synonyms:
- 5,6,7-Trihydroxyflavone
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 1G |
NT$4,914
|
6 | 4 | It can be shipped in about 2 weeks after ordering | |
| 5G |
NT$15,708
|
11 | 0 | Contact Us |
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* The storage conditions are subject to change without notice.
| Product Number | T2721 |
| Purity / Analysis Method | >98.0%(T) |
| Molecular Formula / Molecular Weight | C__1__5H__1__0O__5 = 270.24 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature | Refrigerated (0-10°C) |
| Condition to Avoid | Heat Sensitive |
| Packaging and Container | 1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 491-67-8 |
| Reaxys Registry Number | 272683 |
| PubChem Substance ID | 125307744 |
| Merck Index (14) | 942 |
| MDL Number | MFCD00017459 |
Specifications
| Appearance | Light yellow to Amber to Dark green powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 265 °C |
| Solubility (soluble in) | Dimethylformamide |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H315 : Causes skin irritation. H319 : Causes serious eye irritation. |
| Precautionary Statements | P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. |
Related Laws:
| RTECS# | DJ3100898 |
Transport Information:
| H.S.code* | 2932.99-000 |
Application
Efflux pump research
Baicalein has been reported to inhibit TetK tetracycline efflux pump.1) The compound also showed synergy with tetracycline in a MRSA strain that doesn’t possess tetK, or with β-lactams.
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- 1) Remarkable Synergies between Baicalein and Tetracycline, and Baicalein and β-Lactams against Methicillin-Resistant Staphylococcus aureus
- Baicalein Inhibits Staphylococcus aureus Biofilm Formation and the Quorum Sensing System In Vitro
- Virtual screening for novel quorum sensing inhibitors to eradicate biofilm formation of Pseudomonas aeruginosa
- Biological properties of baicalein in cardiovascular system (a review)
- New therapeutic aspects of flavones: the anticancer properties of Scutellaria and its main active constituents Wogonin, Baicalein and Baicalin (a review)
- Therapeutic potentials of baicalin and its aglycone, baicalein against inflammatory disorders (a review)
Application
Quorum sensing research / Biofilm research
References
Application
Baicalein: A Flavonoid with Various Pharmacological Activities Including Antioxidant and Anti-Tumor Activities
Baicalein is a flavonoid and one of the major constituent of the root of Scutellaria baicalensis, as well as wogonin [W0010] and baicalin [B2835]. Baicalein possesses a multitude of pharmacological activities. It has been reported that baicalein is a potent free radical scavenger and xanthine oxidase inhibitor, thus improving endothelial function and conferring cardiovascular protective actions against oxidative stress-induced cell injury. Furthermore, baicalein has potent anti- inflammatory and anti-tumor activities. Baicalein is cytotoxic to various human tumor cell lines in vitro and inhibit tumor growth in vivo. (The product is for research purpose only.)
References
PubMed Literature
Articles/Brochures
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Specifications
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