Maintenance Notice (0:30 AM July 19 - 1:30 AM July 21, 2025 UTC): This website is scheduled to be unavailable due to maintenance. Maintenance may be completed earlier than scheduled. We appreciate your patience and understanding.
Product Document Searching Made Easy by 2D Code! | TCI Materials Science News July 2025 | [Product Highlights] Travoprost with Intra-Ocular-... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 138046-43-2 | Product Number: Y0032
YM-750
×
![]()
×
New
Purity: >93.0%(HPLC)(qNMR)
Synonyms:
- 1-[(9H-Fluoren-2-yl)methyl]-1-cycloheptyl-3-mesitylurea
- 1-Cycloheptyl-1-(9H-fluoren-2-ylmethyl)-3-mesitylurea
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 20MG |
NT$5,754
|
30 | 0 | It can be shipped in about 2 weeks after ordering |
* The above prices include freight cost, customs, and other charges to the destination except for products that need to be shipped by sea or dry ice. For details, please contact
our distributor
in Taiwan to order our product.
* The storage conditions are subject to change without notice.
| Product Number | Y0032 |
Purity / Analysis Method 
|
>93.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__3__1H__3__6N__2O = 452.64 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 138046-43-2 |
| Reaxys Registry Number | 8368179 |
| MDL Number | MFCD00905424 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 93.0 area% |
| Purity(qNMR) | min. 93.0 % |
| Melting point | 96.0 to 100.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 99 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2924.29-000 |
Application
YM-750: A Potent and Selective Inhibitor of Acyl-Coenzyme A
Acyl-Coenzyme A (ACAT, also known as sterol O-acyltransferase or SOAT) is an intracellular enzyme that catalyzes the formation of cholesteryl esters from cholesterol and fatty acyl-CoA.1) Recently, many studies have suggested that ACAT-1 (SOAT-1) plays a critical role in cancer initiation and progression and is an attractive target for novel anticancer therapies.2) This product, YM-750, is a potent and selective inhibitor of ACAT.1,3,4) (The product is for research use only.)
References
- 1) Targeting Sterol O-Acyltransferase/Acyl-CoA:Cholesterol Acyltransferase (ACAT): A Perspective on Small-Molecule Inhibitors and Their Therapeutic Potential (a review)
- 2) Cholesterol metabolism: New functions and therapeutic approaches in cancer (a review)
- 3) YM750, an ACAT Inhibitor, Acts on Adrenocortical Cells to Inhibit Aldosterone Secretion Due to Depolarization
- 4) Effects of an anti-oxidative ACAT inhibitor on apoptosis/necrosis and cholesterol accumulation under oxidative stress in THP-1 cell-derived foam cells
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.