Diazirine changes to a high-reactive carbene by absorbing light near 360 nm, which forms a covalent bond to a nearby molecule. The covalent bond is more stable than one formed by nitrene derived from a photoreactive azide.
Phenyldiazirine derivatives 1–3 have a functional group at the para position. For example, after the functional group attaches to a ligand, the diazirine group reacts with the acceptor molecule under photoexcitation. It has been reported in research of the photoaffinity labelings which include the crosslinker with peptides or sugars,2) and the photoaffinity microarrays.3)
Maintenance Notice (10:00 PM July 18 - 1:00 AM July 21, 2025 UTC): This website is scheduled to be unavailable due to maintenance. Maintenance may be completed earlier than scheduled. We appreciate your patience and understanding.
Product Document Searching Made Easy by 2D Code! | TCI Materials Science News July 2025 | [Product Highlights] Travoprost with Intra-Ocular-... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
