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CAS RN: 3562-84-3 | 產品號碼: B4099
產品號碼 | B4099 |
純度/分析方法 | >98.0%(GC)(T) |
分子式 / 分子量 | C__1__7H__1__2Br__2O__3 = 424.09 |
外觀與形狀(20°C) | Solid |
儲存條件 | Room Temperature (Recommended in a cool and dark place, <15°C) |
包裝和容器 | 1G-Glass Bottle with Plastic Insert (閲覽圖片) |
CAS RN | 3562-84-3 |
Reaxys-RN | 273668 |
PubChem Substance ID | 253661712 |
Merck Index(14) | 1065 |
MDL編號 | MFCD00078962 |
產品規格
Appearance | White to Light yellow powder to crystal |
Purity(GC) | min. 98.0 % |
Purity(Neutralization titration) | min. 98.0 % |
Melting point | 150.0 to 154.0 °C |
性質
熔點 | 152 °C |
GHS
圖形表示 |
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信號詞 | Danger |
危險性說明 | H301 : Toxic if swallowed. |
防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P270 : Do not eat, drink or smoke when using this product. P264 : Wash skin thoroughly after handling. P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth. P405 : Store locked up. |
相關法規
RTECS # | OB1804200 |
運輸資料
UN編號 | UN2811 |
類別 | 6.1 |
包裝類別 | III |
HS編碼* | 2932.99-000 |
Application
Benzbromarone: An Inhibitor of Xanthine Oxidase (XO) and Cytochrome P450 2C9 (CYP2C9)
Benzbromarone is a benzofuran derivative and non-competitive inhibitor of xanthine oxidase (XO). Benzbromarone reduces the production of uric acid, increases the excretion of uric acid through the kidneys and used in the treatment of gout. It is a very potent inhibitor of cytochrome P450 2C9 (CYP2C9). (The product is for research purpose only.)
References
- Benzbromarone: a review of its pharmacological properties and therapeutic use in gout and hyperuricemia
- Potentiation of anticoagulant effect of warfarin caused by enantioselective metabolic inhibition by the uricosuric agent benzbromarone
- Mechanisms of benzarone and benzbromarone-induced hepatic toxicity
考研文獻
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