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Product Document Searching Made Easy by 2D Code! | TCI Life Science News July 2026 | [Product Highlights] Mitochondrial Membrane Potential... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
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CAS RN: 114-07-8 | 產品號碼: E0751
補充產品訊息:
This product has not been tested for potency and is guaranteed for chemical purity.
| 產品號碼 | E0751 |
純度/分析方法 
|
>98.0%(T) |
| 分子式 / 分子量 | C__3__7H__6__7NO__1__3 = 733.94 |
| 外觀與形狀（20°C） | Solid |
| 儲存條件
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Hygroscopic |
| CAS RN | 114-07-8 |
| Reaxys-RN | 75279 |
| PubChem Substance ID | 87559996 |
| Merck Index(14) | 3681 |
| MDL編號 | MFCD00084654 |
產品規格
| Appearance | White to Orange to Green powder to crystal |
| Purity(Nonaqueous Titration) | min. 98.0 %(calcd.on anh.substance) |
| Specific rotation [a]20/D | -71.0 to -78.0 deg(C=2, EtOH)(calcd.on anh.substance) |
| Water | max. 10.0 % |
性質
| 比旋光 [α]D | -74° (C=2,EtOH) |
| 溶解性（可溶於） | Ether, 1,2-Dichloroethane |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H317 : May cause an allergic skin reaction. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
相關法規
| RTECS # | KF4375000 |
運輸資料
| HS編碼* | 2941.50-000 |
Application
Biofilm research
Susceptibility of Actinobacillus actinomycetemcomitans, strain 310a, biofilm to erythromycin has been reported.1) Adding 10 mg/L of the antibiotic reduced biofilm development in the early phase, but it enhanced biofilm development in the mature phase.
(The product is for research purpose only.)
(The product is for research purpose only.)
Reference
- Susceptibility of Actinobacillus actinomycetemcomitans to six antibiotics decreases as biofilm matures
- Erythromycin (a review)
- The macrolides: erythromycin, clarithromycin, and azithromycin (a review)
- Erythromycin resistance by ribosome modification (a review)
- Erythromycin and other macrolides as prokinetic agents (a review)
- Macrolides: from in vitro anti-inflammatory and immunomodulatory properties to clinical practice in respiratory diseases (a review)
Application
Erythromycin: The First Macrolide Antibiotic
Macrolide antibiotics are classified by the size of the macrocyclic lactone ring of aglycone as 14-, 15- or 16-membered ring macrolides. Macrolides are characterized by similar chemical structures, mechanisms of action and resistance, but vary in the different pharmacokinetic parameters, and spectrum of activity. Erythromycin (abbrev: EM), the first 14-membered macrolide, is isolated from a strain of the actinomycete Saccharopolyspora erythraea. EM has activity against a wide range of Gram-positive bacteria including Streptococcus and Staphylococcus, and limited activity against Gram-negative bacteria. EM inhibits protein synthesis in susceptible organisms by binding to specific nucleotides in 23S rRNA within the 50S subunit of the bacterial ribosome. EM and macrolides also shows gastrointestinal motor stimulating activity as a motilin-agonist, and anti-inflammatory or immunomodulatory activity. EM is easily inactivated by gastric acid. Therefore, a number of more stable macrolides such as azithromycin [A2076] and clarithromycin [C2220] have been chemically synthesized from EM.
References
PubMed Literature
文檔
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