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CAS RN: 26116-56-3 | 產品號碼: E1555
Erythromycylamine
純度/分析方法: >90.0%(qNMR)
别名:
- (9S)-9-Amino-9-deoxoerythromycin
- 9(S)-Erythromycylamine
- (3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-10-Amino-6-[[(2S,3R,4S)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy]-14-ethyl-7,12,13-trihydroxy-4-[[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy]-3,5,7,9,11,13-hexamethyloxacyclotetradecan-2-one
文件:
* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與
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* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準,敬請留意。
補充產品訊息:
This product has not been tested for potency and is guaranteed for chemical purity.
| 產品號碼 | E1555 |
純度/分析方法
|
>90.0%(qNMR) |
| 分子式 / 分子量 | C__3__7H__7__0N__2O__1__2 = 734.97 |
| 外觀與形狀(20°C) | Solid |
儲存條件
|
Frozen (-20°C) |
| 儲存在惰性氣體下 | Store under inert gas |
| 應避免的情況 | Air Sensitive,Heat Sensitive |
包裝和容器
|
200MG-Glass Bottle with Plastic Insert (閲覽圖片) |
| CAS RN | 26116-56-3 |
| Reaxys-RN | 4241492 |
| MDL編號 | MFCD00872156 |
產品規格
| Appearance | White to Light yellow powder to crystal |
| Purity(qNMR) | min. 90.0 % |
| Specific rotation | -45.0 to -49.0 deg(C=1, CHCl3) |
| NMR | confirm to structure |
性質
| 熔點 | 129 °C |
| Degree of solubility in water | 1.22 g/l 20 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Danger |
| 危險性說明 | H318 : Causes serious eye damage. H410 : Very toxic to aquatic life with long lasting effects. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P273 : Avoid release to the environment. P280 : Wear eye protection/ face protection. P391 : Collect spillage. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. |
相關法規
| RTECS # | KF4590000 |
運輸資料
| UN編號 | UN3077 |
| 類別 | 9 |
| 包裝類別 | III |
| HS編碼* | 2941.50-000 |
Application
Erythromycylamine: An Active Metabolite of a Macrolide Antibiotic Dirithromycin
Erythromycylamine is the major active metabolite of dirithromycin [D5495], derived from a macrolide antibiotic erythromycin [E0751].1) Erythromycylamine has excellent activity against Campylobacter, a type of bacteria that can cause diarrheal disease.2) (The product is for research purpose only.)
References
- 1) Synthesis and antimicrobial evaluation of dirithromycin (ASE 136; LY237216), a new macrolide antibiotic derived from erythromycin
- 2) Comparative in vitro activities of new 14-, 15-, and 16-membered macrolides
- 3) Quantitative determination of erythromycylamine in human plasma by liquid chromatography-mass spectrometry and its application in a bioequivalence study of dirithromycin
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