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CAS RN: 2216-51-5 | 產品號碼: M0545
補充產品訊息:
Synonym: l-Menthol
產品規格
| Appearance | White or Colorless powder to crystal |
| Purity(GC) | min. 99.0 % |
| Optical purity(GC) | min. 99.0 ee% |
| Melting point | 42.0 to 45.0 °C |
性質
| 熔點 | 43 °C |
| 沸點 | 216 °C |
| 比旋光 [α]D | -50° (C=10,EtOH) |
| 水溶性 | Insoluble |
| Degree of solubility in water | 490 mg/l 25 °C |
GHS
| 圖形表示 |
|
| 信號詞 | Warning |
| 危險性說明 | H315 : Causes skin irritation. H319 : Causes serious eye irritation. H336 : May cause drowsiness or dizziness. H402 : Harmful to aquatic life. |
| 防範說明 | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P273 : Avoid release to the environment. P271 : Use only outdoors or in a well-ventilated area. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ eye protection/ face protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P337 + P313 : If eye irritation persists: Get medical advice/ attention. P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 + P364 : Take off contaminated clothing and wash it before reuse. P332 + P313 : If skin irritation occurs: Get medical advice/ attention. P304 + P340 + P312 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell. P403 + P233 : Store in a well-ventilated place. Keep container tightly closed. P405 : Store locked up. |
相關法規
| RTECS # | OT0700000 |
運輸資料
| HS編碼* | 2906.11-000 |
Application
(-)-Menthol: A Monocyclic Monoterpene Alcohol exhibiting Many Bioactivities
(±)-Menthol [M0321] is a monocyclic monoterpene alcohol found in peppermint which is known to exhibit biological activity such as antibacterial, antifungal, antipruritic, anticancer and analgesic effects. (±)-Menthol is widely used as a product in cosmetics, a flavoring agent, and a synthetic intermediate. (±)-Menthol is a racemic mixture of the (-)-menthol and (+)-menthol [M3170]. (-)-Menthol is more common than (+)-menthol in nature, and exhibits, antibacterial, anticancer, and analgesic properties, as well as inhibits cholinesterase. In contrast, (+)-menthol has antifungal activity, but does not exhibit antibacterial, anticancer, analgesic properties, or cholinesterase inhibitory activities.1) It has been reported that menthol's characteristic pleasant cooling sensation is due to the activation of sensory neurons generally termed transient receptor potential (TRP) channels, in particular transient receptor potential melastatin family member 8 (TRPM8) and transient receptor potential subfamily ankyrin 1 channel (TRPA1).2-4) (The product is for research purpose only.)
References
- 1) Menthol: A simple monoterpene with remarkable biological properties (a review)
- 2) Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
- 3) The transient receptor potential channel TRPA1: from gene to pathophysiology (a review)
- 4) TRPA1 (a review)
PubMed Literature
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