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CAS RN: 220620-09-7 | 產品號碼: T3589

Tigecycline


纯度/分析方法: >98.0%(HPLC)
別名
  • 9-tert-Butylglycylamidominocycline
文件:
100MG
NT$3,640
≥60  0   下單後約3-4週內可以出貨
500MG
NT$12,560
32   0   下單後約3-4週內可以出貨

* 以上價格已含運費關稅等但一些需要海運以及乾冰運輸的產品除外,詳情請與 當地經銷商 洽詢。
* TCI會時常優化儲存條件,儲存溫度請以在線目錄為準,敬請留意。


產品號碼 T3589
純度/分析方法 >98.0%(HPLC)
分子式 / 分子量 C__2__9H__3__9N__5O__8 = 585.66 
外觀與形狀(20°C) Solid
儲存條件 Frozen (<0°C)
應避免的情況 Heat Sensitive
包裝和容器 100MG-Glass Bottle with Plastic Insert (閲覽圖片),  500MG-Glass Bottle with Plastic Insert (閲覽圖片)
CAS RN 220620-09-7
Reaxys-RN 8379453
PubChem Substance ID 354335260
Merck Index(14) 9432
MDL編號

MFCD00935753

產品規格
Appearance Light yellow to Brown powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 97.0 %
Specific rotation [a]20/D -189 to -208 deg(C=0.15, methanol)
NMR confirm to structure
性質
熔點 185 °C(dec.)
比旋光 [α]D -199° (C=0.15,CH3OH)
水溶性 Soluble
GHS
圖形表示 Pictogram Pictogram Pictogram
信號詞 Danger
危險性說明 H318 : Causes serious eye damage.
H360 : May damage fertility or the unborn child.
H410 : Very toxic to aquatic life with long lasting effects.
防範說明 P501 : Dispose of contents/ container to an approved waste disposal plant.
P273 : Avoid release to the environment.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P391 : Collect spillage.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor.
P405 : Store locked up.
相關法規
RTECS # QI7619500
運輸資料
UN編號 UN3077
類別 9
包裝類別 III
HS編碼* 2941.30-000
*此H.S.編碼用於日本出口報關, 不適用於您所在國家或地區的進口申報
Application
Tigecycline: The First Glycylcycline Antimicrobial Agent with Activity against Multidrug-Resistant Strains

Tigecycline (GAR-936) is the first glycylcycline antimicrobial agent with expanded broad-spectrum activity against both Gram-negative (except for Pseudomonas aeruginosa) and Gram-positive aerobes and anaerobes. Furthermore, the spectrum of activity extends to multidrug-resistant strains of Staphylococcus aureus (MRSA), Streptococcus pneumoniae, vancomycin-resistant enterococci (VRE), and Enterobacteriaceae, including extended-spectrum β-lactamase (ESBL) producing strains. In addition, tigecycline is able to overcome the major resistance mechanisms, ribosomal protection and efflux. Tigecycline inhibits protein translation in bacteria by binding to the 30S ribosomal subunit and blocking entry of aminoacyl-tRNA molecules into the A site of the ribosome. Tigecycline binds to bacterial ribosomes in a novel way that allows it to overcome tetracycline resistance due to ribosomal protection. (The product is for research purpose only.)

References


考研文獻


TCIMail
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