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Synthesis of Trichostatin A

TCI is able to respond to multistep reactions and technical strength to improve the synthetic route. One example of this is demonstrated through the synthesis of Trichostatin A.
Through development of optical conditions, a 20 step synthesis was shortened to 9 steps.

 

Before Improvement

Synthesis of trichostatin A before improvement

 Develop the condition of optical resolution
 

After Improvement

Synthesis of trichostatin A after Improvement


Listed codes in brackets in reaction scheme are TCI's product codes. Our over 30,000 products can be used as raw materials for custom synthesis.
 
  
 
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