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CAS RN: 280744-09-4 | Product Number: B5716

SB 216763

Purity: >98.0%(HPLC)
  • 3-(2,4-Dichlorophenyl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione
1   1   ≥20 
Contact Us Contact Us ≥20 

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Product Number B5716
Purity / Analysis Method >98.0%(HPLC)
Molecular Formula / Molecular Weight C__1__9H__1__2Cl__2N__2O__2 = 371.22  
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Condition to Avoid Heat Sensitive
CAS RN 280744-09-4
Reaxys Registry Number 11333014
PubChem Substance ID 354335732
MDL Number


Appearance Light yellow to Brown powder to crystal
Purity(HPLC) min. 98.0 area%
Properties (reference)
Melting Point 104 °C
Related Laws:
Transport Information:
HS Number 2933.99.8290
SB 216763: An ATP-Competitive Inhibitor of GSK-3α

SB 216763 is reportedly an ATP-competitive inhibitor of glycogen synthase kinase-3α (GSK-3α) in vitro with an IC50 value of 34 nM. GSK-3 is a serine/threonine protein kinase, and inhibition of its activity has been proposed to play a role in the regulation of numerous signalling pathways that elicit cellular responses.


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