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CAS RN: 32222-06-3 | Product Number: C3078

Calcitriol


Purity: >97.0%(HPLC)
Synonyms:
  • 1α,25-Dihydroxyvitamin D3
  • 1,25-Dihydroxycholecalciferol
Documents:
1MG
$659.00
1   1   19  

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Product Number C3078
Purity / Analysis Method >97.0%(HPLC)
Molecular Formula / Molecular Weight C__2__7H__4__4O__3 = 416.65  
Physical State (20 deg.C) Solid
Storage Temperature <0°C
Store Under Inert Gas Store under inert gas
Condition to Avoid Air Sensitive,Heat Sensitive
CAS RN 32222-06-3
Reaxys Registry Number 2227647
PubChem Substance ID 354333875
Merck Index (14) 1644
MDL Number

MFCD00867079

Specifications
Appearance White to Almost white powder to crystal
Purity(HPLC) min. 97.0 area%
Properties (reference)
Melting Point 119 °C
Maximum Absorption Wavelength 265 nm
GHS
Pictogram Pictogram Pictogram
Signal Word Danger
Hazard Statements H300 + H310 + H330 : Fatal if swallowed, in contact with skin or if inhaled.
H361 : Suspected of damaging fertility or the unborn child.
Precautionary Statements P501 : Dispose of contents/ container to an approved waste disposal plant.
P260 : Do not breathe dust/ fume/ gas/ mist/ vapors/ spray.
P270 : Do not eat, drink or smoke when using this product.
P262 : Do not get in eyes, on skin, or on clothing.
P202 : Do not handle until all safety precautions have been read and understood.
P201 : Obtain special instructions before use.
P271 : Use only outdoors or in a well-ventilated area.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection.
P284 : Wear respiratory protection.
P308 + P313 : IF exposed or concerned: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
P301 + P310 + P330 : IF SWALLOWED: Immediately call a POISON CENTER/doctor. Rinse mouth.
P302 + P350 + P310 : IF ON SKIN: Gently wash with plenty of soap and water. Immediately call a POISON CENTER or doctor/ physician.
P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor.
P403 + P233 : Store in a well-ventilated place. Keep container tightly closed.
P405 : Store locked up.
Related Laws:
Transport Information:
UN Number (DOT-AIR) UN2811
Class (DOT-AIR) 6.1
Packing Group (TCI-A) I
HS Number 2936.29.5020
Application
Calcitriol: The Active Form of Vitamin D3

Calcitriol (1α,25-dihydroxyvitamin D3) is the active form of vitamin D3 (cholecalciferol) [C0314]. The natural supply of vitamin D3 in human being mainly depends on ultraviolet light for conversion of 7-dehydrocholesterol [CAS: 434-16-2] to vitamin D3 in the skin. The transformation (hydroxylation) of vitamin D3 is catalyzed by enzymes in the liver and the kidney to produce calcitriol, the active form of vitamin D3. Calcitriol is active in the regulation of the absorption of calcium from the gastrointestinal tract. In addition, in vitro and in vivo studies have shown that calcitriol directly suppresses secretion and synthesis of parathyroid hormone (PTH). (The product is for research purpose only.)

References


PubMed Literature


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