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Maintaining the undifferentiated state of hiPS cell
Sulfated hyaluronic acid maintains the undifferentiated state of hiPS cells underfeeder-free and bFGF-free conditions.
These data were kindly provided by Prof. Shoko Nishihara and Dr. Taichi Miura, Soka University.
Reference
- Highly sulfated hyaluronic acid maintains human induced pluripotent stem cells under feeder-free and bFGF-free conditions
Stabilization of bFGF
Low- and high- sulfated hyaluronic acid were individually added to bFGF and incubated at 37°C for 3 days,
followed by SDS-PAGE and image analysis to calculate the bFGF content.
High-sulfated hyaluronic acid has a greater capacity to preserve bFGF than heparin.
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