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Currently, the development of radiopharmaceuticals is advancing. In particular, the field of theranostics, which integrates diagnostics and therapeutics by selectively applying radionuclides according to their use, is attracting significant attention and undergoing active research and development.1)
We offer bifunctional chelators (BFCs) which are suitable for theranostic research. Our BFCs contain DOTA, a widely used chelating agent, as well as NODAGA, which enables efficient metal chelation under milder conditions such as lower temperatures and shorter reaction times.2)
For conjugation with carrier molecules such as peptides and antibodies,3) we provide BFCs equipped with functional groups such as click chemistry (azido group, DBCO, TCO), as well as suitable for reactions with amines and thiols (NHS ester moiety and maleimide group).
Products
DOTA Derivatives
NODAGA Derivatives
Related Products
References
- 1) The Chemical Scaffold of Theranostic Radiopharmaceuticals: Radionuclide, Bifunctional Chelator, and Pharmacokinetics Modifying Linker
- 2) Matching chelators to radiometals for radiopharmaceuticals
- 3) Recent developments in bioorthogonal chemistry and the orthogonality within
