Conventional polymers have long relied heavily on petroleum-derived feedstocks due to their low cost and ease of processing. However, growing concerns over environmental pollution and climate change caused by petroleum-based materials have accelerated interest in bio-based polymers as a promising alternative to address these challenges.1-3) Furthermore, in recent years, increasing geopolitical risks, including tensions in the Middle East, have highlighted the instability of petroleum supply. As a result, the transition toward alternative feedstocks from a resource security perspective is becoming increasingly important. Against this backdrop, bio-based materials derived from renewable resources such as plants are expected to offer a viable solution that simultaneously reduces environmental impact and improves supply stability. These materials are also essential for achieving a sustainable society and play an increasingly important role in meeting the goals of the SDGs.
Poly(lactic acid) (= PLA) is one of the most well-known biodegradable polymers.4) It is synthesized via ring-opening polymerization of lactide, which is derived from starch-based biomass such as corn. Because the plant-based raw materials have already absorbed atmospheric carbon dioxide during their growth, the disposal of PLA does not result in a net increase in CO2 emissions. In addition, its degradation products —water and carbon dioxide— are harmless to the environment. Owing to these characteristics, PLA has attracted significant attention as a green plastic and is widely used in applications such as disposable packaging containers and compostable agricultural mulch films. Furthermore, to improve its physical properties, extensive research has been conducted on composite materials incorporating natural polymers (e.g., cellulose) and inorganic fillers.4)
PLA is also widely utilized in biomedical applications due to its excellent biocompatibility and mechanical strength.5) It is used in various medical devices, including scaffolds for bone regeneration and absorbable sutures. Moreover, compared to poly(lactic-co-glycolic acid) (= PLGA), PLA exhibits slower biodegradation and lower water absorption, enabling more precise control over drug release rates.6) As a result, it is used in controlled-release systems such as microspheres and drug delivery systems for applications including hormone therapy for cancer, as well as in dental and cosmetic treatments.
We offer a comprehensive lineup of six PLA products, including both poly(L-lactic acid) and poly(DL-lactic acid), each available in three different average molecular weights: approximately 100000, 200000, and 300000. All products are synthesized from corn-derived raw materials. Poly(L-lactic acid) is a semi-crystalline polymer with excellent mechanical strength, whereas poly(DL-lactic acid) is amorphous and exhibits higher flexibility and water absorption, resulting in a faster degradation rate.
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