CAS RN: 188062-50-2 | Product Number: A3532

Abacavir Sulfate

Purity: >95.0%(T)(HPLC)

Synonyms:

Abacavir Hemisulfate
[(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol Hemisulfate

Product Documents:

Size	Unit Price	Same Day	2-3 Business Days	Other Lead Time	Shipping Information
1G	$100.00	20	3	Contact Us	Shipping Simulation

* Please contact our distributors or TCI to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.

General Information plus

Product Number	A3532
Purity / Analysis Method	>95.0%(T)(HPLC)
Molecular Formula / Molecular Weight	C__2__8H__3__6N__1__2O__2·H__2O__4S = 670.75
Physical State (20 deg.C)	Solid
Storage Temperature	Refrigerated (0-10°C)
Store Under Inert Gas	Store under inert gas
Condition to Avoid	Air Sensitive,Hygroscopic,Heat Sensitive
Packaging and Container	1G-Glass Bottle with Plastic Insert (View image)
CAS RN	188062-50-2
Reaxys Registry Number	10402665
MDL Number	MFCD04112763

Specifications & Properties plus

Specifications

Appearance	White to Light yellow to Light orange powder to crystal
Purity(HPLC)	min. 95.0 area%
Purity(Volumetric Analysis)	min. 95.0 %
Specific rotation	-38.0 to -42.0 deg(C=0.5, methanol)
Water	max. 1.0 %
NMR	confirm to structure

Properties (reference)

Solubility in water	Soluble
Degree of solubility in water	77,000 mg/l 25 °C

Safety & Regulations plus

GHS

Pictogram
Signal Word	Danger
Hazard Statements	H361 : Suspected of damaging fertility or the unborn child. H317 : May cause an allergic skin reaction. H334 : May cause allergy or asthma symptoms or breathing difficulties if inhaled. H341 : Suspected of causing genetic defects.
Precautionary Statements	P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P272 : Contaminated work clothing should not be allowed out of the workplace. P202 : Do not handle until all safety precautions have been read and understood. P201 : Obtain special instructions before use. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 : Wear respiratory protection. P302 + P352 : IF ON SKIN: Wash with plenty of water. P308 + P313 : IF exposed or concerned: Get medical advice/ attention. P362 + P364 : Take off contaminated clothing and wash it before reuse. P304 + P340 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. P405 : Store locked up.

Related Laws:

Transport Information:

H.S.code*

2933.59-000

*This code is applied to the products when TCI exports from Japan and not for import in your country.

Applications & Literature plus

Application

Abacavir Sulfate: A Nucleoside Analog Reverse Transcriptase Inhibitor (RTI)

Abacavir sulfate (1592U89 sulfate), a sulfate salt form of abacavir [A2694], is a nucleoside reverse transcriptase inhibitor (RTI) that inhibits HIV-1 in vitro with a potency similar to that of zidovudine [A2052]. Abacavir is converted by cellular enzymes to the active metabolite, carbovir triphosphate (CBV-TP) which is an analogue of deoxyguanosine-5’-triphosphate (dGTP). CBV-TP is incorporated into the virus DNA strand in place of dGTP, and inhibits the activity of HIV-1 reverse transcriptase (RT) both by competing with the natural substrate dGTP. (The product is for research purpose only.)