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CAS RN: 81732-46-9 | Product Number: B4564
Bambuterol Hydrochloride
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Purity: >96.0%(T)(HPLC)
Synonyms:
Product Documents:
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| Product Number | B4564 |
Purity / Analysis Method 
|
>96.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__2__9N__3O__5·HCl = 403.90 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Packaging and Container
|
1G-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 81732-46-9 |
| Related CAS RN
|
81732-65-2 |
| Reaxys Registry Number | 9451479 |
| PubChem Substance ID | 253662217 |
| Merck Index (14) | 953 |
| MDL Number | MFCD03427293 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(HPLC) | min. 96.0 area% |
| Purity(Nonaqueous Titration) | min. 96.0 % |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 225 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2924.29-000 |
Application
Bambuterol: A Long-Acting Prodrug of the β2 Adrenergic Agonist Terbutaline
Bambuterol is a long-acting biscarbamate ester prodrug of the β2 adrenergic agonist (R,S)-terbutaline. Bambuterol is hydrolyzed to (R,S)-terbutaline primarily by butyrylcholinesterase. R-Terbutaline is more active form than S-terbutaline. Bambuterol is used for treatment of asthma. (The product is for research purpose only.)
References
- Bambuterol, a carbamate ester prodrug of terbutaline, as inhibitor of cholinesterases in human blood
- Hydrolysis of 3H-bambuterol, a carbamate prodrug of terbutaline, in blood from humans and laboratory animals in vitro
- Clinical pharmacokinetics of bambute (a review)
- Determination of a basic drug, bambuterol, in human plasma by capillary electrophoresis using double stacking for large volume injection and supported liquid membranes for sample pretreatment
- Quantification of bambuterol hydrochloride in a formulated product using solid-state NMR
- Simultaneous analysis of bambuterol and its active metabolite terbutaline enantiomers in rat plasma by chiral liquid chromatography-tandem mass spectrometry
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