Maintenance Notice (3:00 AM - 8:30 AM November 1, 2025 UTC): This website is scheduled to be unavailable due to maintenance. We appreciate your patience and understanding.
Product Document Searching Made Easy by 2D Code! | TCI Chemistry News October 2025 | [Product Highlights] Tetraphenylethylene Derivatives Used for... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 189279-58-1 | Product Number: D6143
Delafloxacin
×
![]()
×
Purity: >98.0%(T)(HPLC)
Synonyms:
- 1-(6-Amino-3,5-difluoro-2-pyridinyl)-8-chloro-6-fluoro-1,4-dihydro-7-(3-hydroxy-1-azetidinyl)-4-oxo-3-quinolinecarboxylic Acid
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 200MG |
$109.00
|
≥40 | 0 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | D6143 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__8H__1__2ClF__3N__4O__4 = 440.76 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| Packaging and Container
|
200MG-Glass Bottle with Plastic Insert (View image) |
| CAS RN | 189279-58-1 |
| Reaxys Registry Number | 9168989 |
| MDL Number | MFCD09955301 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Neutralization titration) | min. 98.0 % |
| Melting point | 241.0 to 245.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 243 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.39-000 |
Application
Delafloxacin: An Anionic Fluoroquinolone Antibiotic against Levofloxacin-Resistant Strains and MRSA
Delafloxacin (ABT-492) is an anionic fluoroquinolone antibiotic lacking a basic substituent at position 7. Delafloxacin has broad-spectrum bactericidal activity in vitro against Gram-positive and Gram-negative bacteria, including levofloxacin-resistant strains of Streptococcus pneumoniae and methicillin-resistant Staphylococcus aureus (MRSA). The antibacterial activity of delafloxacin is due to inhibition of both bacterial topoisomerase IV and DNA gyrase (topoisomerase II) enzymes, which are required for bacterial DNA replication, transcription, repair, and recombination. (The product is for research purpose only.)
References
- In Vitro Activities of ABT-492, a New Fluoroquinolone, against 155 Aerobic and 171 Anaerobic Pathogens Isolated from Antral Sinus Puncture Specimens from Patients with Sinusitis
- In vitro antibacterial potency and spectrum of ABT-492, a new fluoroquinolone
- Contrasting Effects of Acidic pH on the Extracellular and Intracellular Activities of the Anti-Gram-Positive Fluoroquinolones Moxifloxacin and Delafloxacin against Staphylococcus aureus
- Delafloxacin, a non-zwitterionic fluoroquinolone in Phase III of clinical development: evaluation of its pharmacology, pharmacokinetics, pharmacodynamics and clinical efficacy (a review)
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.