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CAS RN: 100501-62-0 | Product Number: E0888
Ethyl 1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylate
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Purity: >98.0%(GC)
Synonyms:
- 1-Ethyl-6,7,8-trifluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
$50.00
|
2 | 0 | Contact Us | |
| 25G |
$164.00
|
18 | 11 | Contact Us |
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* The storage conditions are subject to change without notice.
| Product Number | E0888 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__4H__1__2F__3NO__3 = 299.25 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive |
| CAS RN | 100501-62-0 |
| Reaxys Registry Number | 4537417 |
| PubChem Substance ID | 160871074 |
| MDL Number | MFCD00276022 |
Specifications
| Appearance | White to Almost white powder to crystal |
| Purity(GC) | min. 98.0 % |
| Melting point | 205.0 to 209.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 207 °C |
GHS
| Pictogram |
|
| Signal Word | Warning |
| Hazard Statements | H317 : May cause an allergic skin reaction. H412 : Harmful to aquatic life with long lasting effects. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P261 : Avoid breathing dust/ fume/ gas/ mist/ vapors/ spray. P273 : Avoid release to the environment. P272 : Contaminated work clothing should not be allowed out of the workplace. P280 : Wear protective gloves. P302 + P352 : IF ON SKIN: Wash with plenty of water. P362 + P364 : Take off contaminated clothing and wash it before reuse. P333 + P313 : If skin irritation or rash occurs: Get medical advice/ attention. |
Related Laws:
Transport Information:
| H.S.code* | 2933.99-000 |
Application
A Synthetic Intermediate of Fluoroquinolone Antibiotics
This product has been used as a synthetic intermediate of fluoroquinolone antibiotics, including lomefloxacin hydrochloride [L0216].
References
- Synthesis and in vitro antimicrobial evaluation of novel fluoroquinolone derivatives
- Synthesis and antibacterial evaluation of novel 8-fluoro Norfloxacin derivatives as potential probes for methicillin and vancomycin-resistant Staphylococcus aureus
- Thermochemical reaction of 7-azido-1-ethyl-6,8-difluoroquinolone-3-carboxylate with heterocyclic amines. An expeditious synthesis of novel fluoroquinolone derivatives
Application
Synthesis of Antibacterial Agents
References
- Hybrid Antibacterials. DNA Polymerase-Topoisomerase Inhibitors
- Pyridonecarboxylic acids antibacterial agents. 11. Intramolecular cyclization of 7-substituted 6-fluoro-1,8-naphthyridine and -quinoline derivatives
- Synthesis and antibacterial evaluation of novel 8-fluoro Norfloxacin derivatives as potential probes for methicillin and vancomycin-resistant Staphylococcus aureus
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