Product Document Searching Made Easy by 2D Code! | TCI Materials Science News November 2025 | [TCIPracticalExample] Ullmann-type Coupling Reaction at Room Temperature... | Various analytical charts can be searched on each product detail page and Product Document Search (The kinds of analytical charts differ by product)
Maximum quantity allowed is 999
Please select the quantity
CAS RN: 73232-52-7 | Product Number: M3504
Methylnaltrexone Bromide
×
![]()
×
Purity: >95.0%(HPLC)(qNMR)
Synonyms:
- 17-(Cyclopropylmethyl)-3,14-dihydroxy-17-methyl-6-oxo-5α-4,5-epoxymorphinan-17-ium Bromide
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 10MG |
$209.00
|
8 | 5 | It can be shipped in about 2 weeks after ordering |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | M3504 |
Purity / Analysis Method 
|
>95.0%(HPLC)(qNMR) |
| Molecular Formula / Molecular Weight | C__2__1H__2__6BrNO__4 = 436.35 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Frozen (-20°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Hygroscopic,Heat Sensitive |
| CAS RN | 73232-52-7 |
| Reaxys Registry Number | 8181088 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 95.0 area% |
| Purity(qNMR) | min. 95.0 % |
| NMR | confirm to structure |
Properties (reference)
GHS
Related Laws:
Transport Information:
| H.S.code* | 2939.19-000 |
Application
Methylnaltrexone Bromide: A Selective μ-Opioid Receptor Antagonist
Methylnaltrexone bromide is a selective antagonist of opioid binding at the μ-opioid receptor, a quaternary derivative of naltrexone [N1176]. As a quaternary amine, methylnaltrexone bromide has greater polarity and lower lipid solubility; therefore, it does not cross the blood-brain barrier.1,2) This allows methylnaltrexone bromide to act as a peripherally-acting μ-opioid receptor antagonist in tissues such as the gastrointestinal tract, thereby reducing the constipating effects of opioids without interfering with opioid-mediated analgesic effects on the central nervous system.3) (The product is for research purpose only.)
References
- 1) Receptor binding, antagonist, and withdrawal precipitating properties of opiate antagonists
- 2) Effects of opiate antagonists and their quaternary derivatives on heroin self-administration in the rat
- 3) Development of peripheral opioid antagonists: new insights into opioid effects (a review)
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.