Maximum quantity allowed is 999
Please select the quantity
CAS RN: 328086-60-8 | Product Number: M3533
Methyl N-(tert-Butoxycarbonyl)-3-[(3S)-2-oxo-3-pyrrolidinyl]-L-alaninate
![Chemical Structure of Methyl N-(tert-Butoxycarbonyl)-3-[(3S)-2-oxo-3-pyrrolidinyl]-L-alaninate](/medias/Tci-440-M3533.jpg?context=bWFzdGVyfHJvb3R8MTk4NjR8aW1hZ2UvanBlZ3xhR1UyTDJnMU1TODVNems0TXpFMk16WTNPVEF5TDFSamFTMDBOREJmVFRNMU16TXVhbkJufGU1ODQ3MmI1OTM0ODg0ZDBhZDVjNzk5YmY3MTIwOWY0OTQzZDVhNWNiMjExNTJlZGVhZGYyMWUyMTRiMGQ1NTI "Methyl N-(tert-Butoxycarbonyl)-3-[(3S)-2-oxo-3-pyrrolidinyl]-L-alaninate")
![Thumbnail of Methyl N-(tert-Butoxycarbonyl)-3-[(3S)-2-oxo-3-pyrrolidinyl]-L-alaninate](/medias/Tci-98-M3533.jpg?context=bWFzdGVyfHJvb3R8MzA2NnxpbWFnZS9qcGVnfGFHRXdMMmcxTkM4NU16azRNekUyTkRBd05qY3dMMVJqYVMwNU9GOU5NelV6TXk1cWNHY3w0YzYwOWY3OGQ4ZDBkZTQzMDdkMGE5ZjJkOTY1ZWUyODBmZmEwMzFiZDYzNGMzNjU2NWI2MWYyYjhhM2VkYTZl)
×
![]()
×
![Methyl N-(tert-Butoxycarbonyl)-3-[(3S)-2-oxo-3-pyrrolidinyl]-L-alaninate](/_ui/responsive/theme-tci/images/missing_product_zoom.jpg "Methyl N-(tert-Butoxycarbonyl)-3-[(3S)-2-oxo-3-pyrrolidinyl]-L-alaninate")
Purity: >98.0%(T)(HPLC)
Synonyms:
- Methyl (S)-2-[(tert-Butoxycarbonyl)amino]-3-[(S)-2-oxopyrrolidin-3-yl]propanoate
- Methyl (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl]propanoate
- (αS,3S)-α-[(tert-Butyloxycarbonyl)amino]-2-oxo-3-pyrrolidinepropanoic Acid Methyl Ester
Product Documents:
| Size | Unit Price | Same Day | 2-3 Business Days | Other Lead Time |
Shipping Information
|
|---|---|---|---|---|---|
| 5G |
$90.00
|
25 | 0 | Contact Us | |
| 25G |
$346.00
|
7 | 0 | Contact Us |
* Please contact our distributors or
TCI
to order our products. The above prices do not include freight cost, customs, and other charges to the destination.
* The storage conditions are subject to change without notice.
| Product Number | M3533 |
Purity / Analysis Method 
|
>98.0%(T)(HPLC) |
| Molecular Formula / Molecular Weight | C__1__3H__2__2N__2O__5 = 286.33 |
| Physical State (20 deg.C) | Solid |
| Storage Temperature
|
Refrigerated (0-10°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Air Sensitive,Heat Sensitive |
| CAS RN | 328086-60-8 |
| Reaxys Registry Number | 8991735 |
| MDL Number | MFCD28138267 |
Specifications
| Appearance | White to Light yellow powder to crystal |
| Purity(HPLC) | min. 98.0 area% |
| Purity(Volumetric Analysis) | min. 98.0 % |
| Melting point | 111.0 to 115.0 °C |
| NMR | confirm to structure |
Properties (reference)
| Melting Point | 114 °C |
GHS
Related Laws:
Transport Information:
| H.S.code* | 2933.79-000 |
Application
A Key Synthetic Intermediate for Antiviral Protease Inhibitors
This product has been used as a key synthetic intermediate for antiviral protease inhibitors including GC376 and nirmatrelvir.
References
- Improved SARS-CoV-2 Mpro inhibitors based on feline antiviral drug GC376: Structural enhancements, increased solubility, and micellar studies
- Alkyne Derivatives of SARS-CoV-2 Main Protease Inhibitors Including Nirmatrelvir Inhibit by Reacting Covalently with the Nucleophilic Cysteine
- Optimized Synthesis of a Key Intermediate of Nirmatrelvir
Product Documents (Note: Some products will not have analytical charts available.)
Safety Data Sheet (SDS)
Please select Language.
The requested SDS is not available.
Please Contact Us for more information.
Specifications
C of A & Other Certificates
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
Sample C of A
This is a sample C of A and may not represent a recently manufactured lot of the product.
A sample C of A for this product is not available at this time.
Analytical Charts
Please enter Lot Number
Incorrect Lot Number. Please input only the 4-5 alphanumeric characters before the hyphen.
The requested analytical chart is not available. Sorry for the inconvenience.