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CAS RN: 33527-91-2 | Product Number: T2898
Tris[2-(dimethylamino)ethyl]amine
![Thumbnail of Tris[2-(dimethylamino)ethyl]amine](/medias/T2898.jpg?context=bWFzdGVyfHJvb3R8MTQ0MDB8aW1hZ2UvanBlZ3xhRGRrTDJnek9TODRPVE0zTURFNU9UazRNak00TDFReU9EazRMbXB3Wnd8MzZmNTI4NGY2ZWNlYWI5NWViZWYzMzRmYjAwZTY3OTc1OTYwYTFmNWI2NjMxYWVkYmVjOGFjNzE4YTRmN2UxOA "Tris[2-(dimethylamino)ethyl]amine")
![Chemical Structure of Tris[2-(dimethylamino)ethyl]amine](/medias/T2898.jpg?context=bWFzdGVyfHJvb3R8NDU4MzZ8aW1hZ2UvanBlZ3xhR1l4TDJoak5pODRPVEl6TlRRNE9EYzJPRE13TDFReU9EazRMbXB3Wnd8OTlkMGZiMGM3ZThlMjU3ZGRlZDYyYmFhODU4NGMwZDYyZTAzOGRjNjVkZjRlNTU2ODExOWE5NDAwZDY1MDE1Zg "Tris[2-(dimethylamino)ethyl]amine")
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![Tris[2-(dimethylamino)ethyl]amine](/_ui/responsive/theme-tci/images/missing_product_zoom.webp "Tris[2-(dimethylamino)ethyl]amine")
Purity: >98.0%(GC)
Synonyms:
- Me6TREN
Product Documents:
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|---|---|---|---|---|---|
| 1G |
$85.00
|
8 | ≥100 | It can be shipped in about 2 weeks after ordering | |
| 5G |
$289.00
|
≥40 | ≥40 | It can be shipped in about 2 weeks after ordering |
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| Product Number | T2898 |
Purity / Analysis Method 
|
>98.0%(GC) |
| Molecular Formula / Molecular Weight | C__1__2H__3__0N__4 = 230.40 |
| Physical State (20 deg.C) | Liquid |
| Storage Temperature
|
Room Temperature (Recommended in a cool and dark place, <15°C) |
| Store Under Inert Gas | Store under inert gas |
| Condition to Avoid | Light Sensitive,Moisture Sensitive |
| CAS RN | 33527-91-2 |
| Reaxys Registry Number | 1758212 |
| PubChem Substance ID | 253659833 |
| MDL Number | MFCD00015607 |
Specifications
| Appearance | Colorless to Light orange to Yellow clear liquid |
| Purity(GC) | min. 98.0 % |
| Purity(Neutralization titration) | min. 96.0 % |
| NMR | confirm to structure |
Properties (reference)
| Boiling Point | 71 °C/0.5 mmHg |
| Flash point | 104 °C |
| Specific Gravity (20/20) | 0.85 |
| Refractive Index | 1.45 |
GHS
| Pictogram |
|
| Signal Word | Danger |
| Hazard Statements | H314 : Causes severe skin burns and eye damage. |
| Precautionary Statements | P501 : Dispose of contents/ container to an approved waste disposal plant. P264 : Wash skin thoroughly after handling. P280 : Wear protective gloves/ protective clothing/ eye protection/ face protection. P303 + P361 + P353 : IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P301 + P330 + P331 : IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P363 : Wash contaminated clothing before reuse. P304 + P340 + P310 : IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/doctor. P305 + P351 + P338 + P310 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. P405 : Store locked up. |
Related Laws:
Transport Information:
| UN Number | UN2735 |
| Class | 8 |
| Packing Group | III |
| H.S.code* | 2921.29-000 |
Application
Me6TREN: A CXC Chemokine Receptor Type 4 (CXCR4) Antagonist
Me6TREN is also known as an antagonist of CXC chemokine receptor type 4 (CXCR4), which is a chemokine receptor expressed on immune cells and cancer cells. CXCR4 is activated by its chemokine ligand CXCL12 (also known as SDF-1), and regulates many physiological and developmental processes such as hematopoietic cell trafficking. .CXCR4 is also one of the main co- receptors for human immunodeficiency virus (HIV) entry into T cells. Recently, it has been reported that CXCR4 induces migration of cancer cells and is important for processes such as metastasis. Therefore, CXCR4 antagonists are expected to regulate these tumor metastatic processes. (The product is for research purpose only.)
References
- Small molecule Me6TREN mobilizes hematopoietic stem/progenitor cells by activating MMP-9 expression and disrupting SDF-1/CXCR4 axis
- A novel molecule Me6TREN promotes angiogenesis via enhancing endothelial progenitor cell mobilization and recruitment
- New molecule for mobilizing marrow stem cells (a review)
- Disrupting the leukemia niche in the central nervous system attenuates leukemia chemoresistance
Application
Atom Transfer Radical Polymerization Using Tris[2-(dimethylamino)ethyl]amine
References
- 1)Activators regenerated by electron transfer for atom transfer radical polymerization of styrene
- 2)Synthesis of high molecular weight poly(styrene-co-acrylonitrile) copolymers with controlled architecture
- 3)Use of ascorbic acid as reducing agent for synthesis of well-defined polymers by ARGET ATRP
- 4)Diminishing catalyst concentration in atom transfer radical polymerization with reducing agents
PubMed Literature
Documents
Product Articles
[TCIMAIL No.161] Multidentate Ligand for Atom Transfer Radical Polymerization[Product Highlights] Atom Transfer Radical Polymerization Using Tris[2-(dimethylamino)ethyl]amine
[Featured Products] Atom Transfer Radical Polymerization (ATRP) and Reversible Addition-Fragmentation Chain-Transfer (RAFT) Polymerization
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