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Synthesis of Trichostatin A

TCI is able to respond to multistep reactions and technical strength to improve the synthetic route. One example of this is demonstrated through the synthesis of Trichostatin A.
Through development of optical conditions, a 20 step synthesis was shortened to 9 steps.

Before Improvement

Synthesis of trichostatin A before improvement

Develop the condition of optical resolution

After Improvement

Synthesis of trichostatin A after Improvement

Listed codes in brackets in reaction scheme are TCI's product codes. Our over 28,000 products can be used as raw materials for custom synthesis.

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