09/22/2014  TCI NEWS

We distribute TCI NEWS every four weeks, to our valued customers using research chemicals and chromatography products.
We hope that you find this helpful for your research.

[NEW] Pamphlet - Multicomponent Reaction (MCR)

TCI now published new pamphlet that collected reagents for Multicomponent Reaction (MCR)!

• MCR examples for introducing multiple substrates in one pot.
• For visual understanding, different colors for each substrate / product are applied.
• A number of building blocks for MCR are listed.

[NEW] TCIMAIL No.162 - Quarterly Magazine

In the TCIMAIL, we mainly introduce our new reagents in the fields of Synthetic Organic Chemistry, Materials Chemistry, Bioscience and Analytical Science.  Examples of application and use are explained in an easy to understand way, using various schemes and charts.  The TCIMAIL also contains technical papers contributed by leading professors and scientists.
TCI Mail No.162

Chemistry Chat
Focusing on the Elements - Molecular Regular Polygons
Mr. Kentaro Sato

Applications
- Useful Cinchona Alkaloid Derived Catalysts
- A Building Block for Organic Electronic Material Incorporating A Reactive 1,2-Diketone Moiety Forming Tetracene Derivatives
- An Ambipolar Organic Semiconductor with Well-Balanced High Hole and Electron Mobility
- Solubility-improved Organic Semiconductor, Thiophene/Phenylene Co-oligomer (TPCO)
- ABBX, A Highly Active Trivalent Iodine Compound for Oxidation Reactions
- γ-Secretase Inhibitor
- Sonic Hedgehog Inhibitor
- Cell Differentiation Research Reagent
- Bone Resorption Inhibitor

TCI Mobile


TCI’s website became usable on smart phones and tablets

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  Structure search is also available

Access to http://www.tcichemicals.com/en/ap/ by your mobile

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Synthetic Organic Chemistry

Research Article

Regioselective Bromination of Fused Pyridine N-Oxides

Baran et al. have reported the regioselective bromination of fused pyridine N-oxides. According to their results, various C2-brominated fused pyridines are produced in high yields with high regioselectivity by using p-toluenesulfonic anhydride as the activator and tetrabutylammonium bromide as the nucleophilic bromide source. This reaction proceeds under mild conditions without commonly-used highly reactive brominating reagents such as Br2 or POBr3. This synthetic method can be incorporated into a viable one-pot oxidation/bromination process, using methyltrioxorhenium/urea hydrogen peroxide as the oxidant. Furthermore, high C2-selective chlorination can be also accomplished by using tetrabutylammonium chloride.
T0054,T1485
M1296,T0054,T1485
T0055,T1485

References

S. E. Wengryniuk, A. Weickgenannt, C. Reiher, N. A. Strotman, K. Chen, M. D. Eastgate, P. S. Baran, Org. Lett. 2013, 15, 792.

New Products

Bioscience

Product Highlight

Zwitterionic Monomer for the Synthesis of Biocompatible Polymers

3-[[2-(Methacryloyloxy)ethyl]dimethylammonio]propionate (CBMA) is a zwitter ionic methacrylate ester with a quaternary ammonium group and a carboxyl group in the molecule. CBMA has been reported to be applied to biomaterials, just like 2-methacryloyloxyethyl phosphorylcholine (MPC) which is well known as a useful monomer for the synthesis of biocompatible polymers. For example, Jiang et al. have added repellency of protein adsorption to a glass surface by polymerizing the CBMA after modifying an atom-transfer radical polymerization (ATRP) initiator on the glass surface.1) Besides, CBMA has been used in the research of polymer modification on a gold surface,2) hydrogel implants resisting the foreign-body reaction,3) and drug delivery vehicles conjugating with an anticancer agent.4)
M2359,M2005

References

1) Z. Zhang, T. Chao, S. Chen, S. Jiang, Langmuir 2006, 22, 10072.
2) Z. Zhang, S. Chen, S. Jiang, Biomacromolecules 2006, 7, 3311.
3) L. Zhang, Z. Cao, T. Bai, L. Carr, J.-R. Ella-Menye, C. Irvin, B. D. Ratner, S. Jiang, Nat. Biotechnol. 2013, 31, 553.
4) Z. Wang, G. Ma, J. Zhang, W. Lin, F. Ji, M. T. Bernards, S. Chen, Langmuir 2014, 30, 3764.

New Products

Chromatography -Analysis of Tranexamic acid by TCI Dual series

TCIDUal
Tranexamic acid is an amino acid analog with high hydrophilicity. However, with TCI Dual series, successful separation can be performed easily without any ion-pair reagents.
This application is also suitable for LC-MS by using volatile buffers.

TCI Catalogs & Product Brochures

websitetip
TCI has a wide variety of specific catalogs and product brochures. Most of them are available in PDF format and can be downloaded from our website.
Please click the following links to pick up the catalogs and brochures you are interested in:

TCI Website Tips

Reagent Guide Online –Product Information Page in TCI Website

TCI Reagent Guides, product catalogs by category, are very useful as reference book for finding reagents. Do you know Reagent Guides are available as online version in our website?
You click “Products” tab, then you can go around our product information by category easily.

Additionally, there are many online version specific features;
-New products that aren’t included in Reagent Guide are added every day.
-Product categories that aren’t included in Reagent Guides are available, and new categories are uploaded on a timely basis.

Please click the following product categories, and find your chemicals!

Exhibitions/Meetings/Shows

The 114th General Meeting of the Korean Chemical Society

Kimdae jung Convention Center
Gwangju, Korea
October 15-17, 2014
» TCI exhibition information      » Event details

2014 RACI National Congress

Adelaide Convention Centre
Adelaide, Australia
December 7-12, 2014
» TCI exhibition information      » Event details

8th Singapore International Chemistry Conference 2014

National University of Singapore
Singapore
December 14-17, 2014
» TCI exhibition information      » Event details

Other Information

TCI Facebook Page

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