8/29/2016  TCI NEWS

We distribute TCI NEWS every four weeks, to our valued customers using research chemicals and chromatography products. We hope that you find this helpful for your research.

[Featured Products] Living Radical Polymerization Reagents

Living radical polymerization is the effective precise polymerization method for high-value added polymers. Recently, a new type of living radical polymerization method that uses organic molecules as catalyst and initiator has been developed. By using this method, polymers with a narrow molecular weight distribution can be synthesized under metal-free condition. This method is expected applied development of the future.

[Brochure] Fluorous Chemistry

It contains the various reagents that are related to fluorous chemistry, one of the research fields of green chemistry.
- A wide variety of fluorous reagents are categorized by functional groups.
- It is also listed many fluorous solvents.

[New Edition] TCIMail Quarterly Magazine – No. 170

Research Articles
Development of Novel P-chiral Phosphorus Ligands for Efficient Transition-Metal Catalyzed Reactions
Guangqing Xu, Assistant Researcher
Wenjun Tang, Professor
State Key Laboratory of Bio-Organic & Natural Products Chemistry,
Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences,

Chemistry Chat
Naming Elements — What Will Be the Name For Element 113?
Kentaro Sato

Applications
-The Smallest “Carbon Nanoring”: [5]Cycloparaphenylene ([5]CPP)
-Isomerically Pure Anthradithiophene Derivatives
-A Safe Cyano(nitro)methylation Reagent
-A New Julia-Type Reagent for Methylenation Reactions
-Stearoyl-CoA Desaturase Inhibitor

Reagent Guides 8th Edition

In these Reagent Guides, TCI products have been classified according to research fields, reaction types, applications and basic structures. Please click here to contact TCI local distributors or TCI for a Free Copy!
Synthetic Organic Chemistry & Materials Chemistry

Classification examples:

Synthetic Organic Chemistry
Asymmetric Organocatalysts / Cross-coupling Reaction Using Transition Metal Catalysts / Condensation & Active Esterification

Materials Chemistry
Solar Cell Research Reagents / OLED / Photochromic Compounds
Bioscience & Analytical Science

Classification examples:

Bioscience
Nucleosides / Amino Acids / Sugars / Lipids / Terpenes / Steroids / Antibodies

Analytical Science
GC Derivatizing Reagents / HPLC Labeling Reagents / HPLC Columns / Derivatization Reagents for MS

Synthetic Organic Chemistry

Research Article

Asymmetric Tandem Michael Addition/Oxidation of Pyrazolones with p-Benzoquinone Using Cinchona Alkaloid Catalysts

Wang et al. have reported the cinchona alkaloid catalysts-promoted asymmetric tandem Michael addition/oxidation of pyrazolones with p-benzoquinone. According to their results, a cinchona alkaloid catalyst of quinine is effective for the reaction to proceed and a wide range of 4,4-disubstituted pyrazol-5-ones are formed with high yields and enantioselectivities. Since pyrazolones are an important class of structural motifs found in a diverse range of biologically active compounds such as antibacterials, this synthetic approach is expected to be applied in the field of drug development.
B0089,B0887,Q0028

References

New Products

Bioscience

Product Highlight

Curcumin Analogs with Enhanced Antitumor Activities

Turmeric containing curcumin, a yellow dye, has been used as a South Asian traditional medicine for hepatobiliary disorders, inflammation, and wound healing. Curcumin has anti-proliferative, cancer-chemopreventive, anti-angiogenic, and anti-oxidant effects. However, its low bioavailability causes limitations of its application to chemotherapy.
GO-Y030 and GO-Y078 are synthetic analogs of curcumin, developed by Shibata, Iwabuchi et al. to increase the antitumor potential and improve the bioavailability.2,3) The assays on various cancer cell lines revealed that GO-Y030 and GO-Y078 suppress tumor cell growth and control the growth-related molecules such as NF- κB, β-catenin, STAT3, c-Myc and IRF-4.4,5) It has been reported that they inhibit in vivo cancer cell growth in a mouse model of gastric cancer and GO-Y078 having a twice higher water-solubility than curcumin is even more effective.5)
C0434,C2302,B4823, H1525

References

New Products

Mixed-Mode columns (ODS + Ion-Exchange) for HPLC “TCI Dual series”

TCI Dual series
Analysis of Organic Acids by TCI Dual series

TCI Catalogs & Product Brochures

websitetip
TCI has a wide variety of catalogs and product brochures. Most of them are available in PDF format and can be downloaded from our website.
Please click the following links to download catalogs and brochures you are interested in.

TCI Website Tips

Reagent Guide - Online Version Available on TCI Website

TCI Reagent Guides, product catalogs by category, are very useful as reference for finding reagents. Do you know Reagent Guides are also available as online version on our website?
You click “Products” tab, then you can go around our product information by category easily.

Additionally, benefits of online catalogs include;
-New products that aren't included in the paper version are added every day.
-Product categories that aren’t included in the paper version are available, and new categories are uploaded timely.

Please click the following product categories, and find your chemicals!

Exhibitions/Meetings/Shows

The 118th General Meeting of the Korean Chemical Society

BEXCO
Busan, Korea
October 12-14, 2016
» TCI exhibition information      » Event details

Other Information

TCI Facebook Page

logo Various chemistry related information, news, and fun content are posted for you.  Visit us and like us on Facebook!

https://www.facebook.com/TCIchemicals

How to Order TCI Products

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Please visit each country/region's website from the following links and confirm the prices.


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