We distribute TCI NEWS every four weeks, to our valued customers using research chemicals and chromatography products. We hope that you find this helpful for your research.

11/22/2017 TCI NEWS

We distribute TCI NEWS every four weeks, to our valued customers using research chemicals and chromatography products. We hope that you find this helpful for your research.


[New Edition] TCIMAIL Quarterly Magazine ? No. 175


TCIMAIL contains technical papers contributed by leading professors and scientists. We also introduce our new reagents in the fields of synthetic organic chemistry, materials chemistry, bioscience and analytical science. Examples of application and use are explained in an easy way, using various schemes and charts.


Research Article
- Silver-Catalyzed CO2 Incorporation Reactions

Tohru Yamada
Professor, Department of Chemistry, Keio University




[NEW Edition] Reagents for Glyco Chemistry & Biology



- Total of 900 products including 200 new products
- Categorized and description of products for easy to understand
- Newly-launched N-glycan (synthetic)
- Many oligosaccharides applicable to sugar-conjugation
- 1H NMR spectral data of 250 products

Request Now


Synthetic Organic Chemistry


[Research Article]
Bicyclo[1.1.1]pentan-1-amine as Bioisostere of Benzene Ring

Baran et al. have reported a scalable synthesis of bicyclo[1.1.1]pentan-1-amine hydrochloride (2) from 1,1-dibromo-2,2-bis(chloromethyl)cyclopropane (1). The small strained bicyclo[1.1.1]pentane strained scaffold is a functionalized bioisostere of a benzene ring and tert-butyl group, and has applications in medicinal chemistry and drug discovery though it’s superior metabolic stabilities, membrane permeability and aqueous solubility compared to phenyl rings. Baran et al. have also have included 1 into the synthesis of various bicyclo[1.1.1]pentane units. This synthetic approach is expected to be applied for the structural optimization of drug candidates.




J. M. Lopchuk, K. Fjelbye, Y. Kawamata, L. R. Malins, C.-M. Pan, R. Gianatassio, J. Wang, L. Prieto, J.Bradow, T. A. Brandt, M. R. Collins, J. Elleraas, J. Ewanicki, W. Farrell, O. O. Fadeyi, G. M. Gallego, J. J. Mousseau, R. Oliver, N. W. Sach, J. K. Smith, J. E. Spangler, H. Zhu, J. Zhu, P. S. Baran, J. Am. Chem. Soc. 2017, 139, 3209.
R. Gianatassio, J. M. Lopchuk, J. Wang, C-M. Pan, L. R. Malins, L. Prieto, T. A. Brandt, M. R. Collins, G. M. Gallego, N. W. Sach, J. E. Spangler, H. Zhu, P. S. Baran, Science 2016351, 241.

» Check for Price and Availability:1,1-Dibromo-2,2-bis(chloromethyl)cyclopropane(Product Number D5290)
» Check for Price and Availability:Bicyclo[1.1.1]pentan-1-amine Hydrochloride(Product Number B5479)


[Product Highlight]
Umemoto's Reagent II : A Powerful and Thermally Stable Trifluoromethylating Agent

Umemoto's reagent II (1), 2,8-diflouro-S-(trifluoromethyl)dibenzothiophenium salt has recently been reported as a new trifluoromethylating agent. Compared to Umemoto’s reagent I (des-fluoro), Umemoto’s reagent II shows superior thermal stability and electrophilicity. Under the basic condition, 1  smoothly reacts with β-dicarbonyl compounds to afford the corresponding trifluoromethylated products. The trifluoromethylation of 1 with terminal alkynes proceeds in the presence of a base and catalytic amounts of copper salts. Furthermore, 1 can be applied to the trifluoromethylation of various nucleophiles such as indoles, thiols and phosphines in the presence of base. 1 is a safe, solid trifluoromethylating agent that it is used for the synthesis of trifluoromethylated compounds which will attract attention in the pharmaceutical community. 




T. Umemoto, B. Zhang, T. Zhu, X. Zhou, P. Zhang, S. Hu, Y. Li, J. Org. Chem. 2017, 82, 7708.

» Check for Price and Availability: Umemoto's Reagent II(Product Number D5335)


New Products




Difluoromethyl 2-Pyridyl Sulfone








Life Science


New Products







Atorvastatin Lactone



Chicoric Acid


Mixed-Mode columns (ODS + Ion-Exchange) for HPLC
“TCI Dual series”


Analysis of Organic Acids by TCI Dual series



» TCI Dual series
» HPLC Applications Index


Reagent Guides 8th Edition


In these Reagent Guides, TCI products have been classified according to research fields, reaction types, applications and basic structures. Please click here to contact TCI local distributors or TCI for a Free Copy!



Synthetic Organic Chemistry &
Materials Chemistry

Classification examples: 

Synthetic Organic Chemistry
Asymmetric Organocatalysts / Cross-coupling Reaction Using Transition Metal Catalysts / Condensation & Active Esterification

Materials Chemistry
Solar Cell Research Reagents / OLED / Photochromic Compounds


Bioscience & Analytical Science

Classification examples: 

Nucleosides / Amino Acids / Sugars / Lipids / Terpenes / Steroids / Antibodies

Analytical Science
GC Derivatizing Reagents / HPLC Labeling Reagents / HPLC Columns / Derivatization Reagents for MS


TCI has a wide variety of catalogs and product brochures. Most of them are available in PDF format and can be downloaded from our website.

» Other Catalogs & Product Brochures


TCI Website Tips 


How to Open Ampule Containers


Is your lab having trouble with ampule safety? TCI created a useful web page showing how to open ampules that reduce breakages, sharps injuries and contamination. Please be sure to review our website for more ampule safety information and share with your colleagues!  


» How to Open Ampule Containers 


Reagent Guide - Online Version Available on TCI Website


TCI Reagent Guides, product catalogs by category, are very useful as reference for finding reagents. Do you know Reagent Guides are also available as online version on our website?
You click “Products” tab, then you can go around our product information by category easily.

Additionally, benefits of online catalogs include;
-New products that aren't included in the paper version are added every day.
-Product categories that aren’t included in the paper version are available, and new categories are uploaded timely.

Please click the following product categories, and find your chemicals!  



» Chemistry


» Materials Science


» Life Science



» Glycoscience


» Analytical Chemistry


» Chromatography Columns




2017 Annual Meeting of Chinese Chemical Society Located in Taipei

National Chiayi University, Taiwan
Dec 1-2, 2017
» TCI exhibition information     » Event details


Organic Chemistry Division of KCS (Korean Chemical Society) Seminar

KIST(Korea Institute of Science and Technology), Seoul, Korea
Dec 8, 2017
» TCI exhibition information     » Event details

Other Information


TCI Facebook Page


Various chemistry related information, news, and fun content are posted for you.  Visit us and like us on Facebook!



How to Order TCI Products

For order, please contact our local distributors as follow.

Countries/ Regions:
South Korea
Other Asia Pacific / Regions


* The prices displayed in the landing website are USD based catalog prices.  TCI has specific website and local currency based price list for customers in South Korea, Singapore, and Australia.  For customers in other Asia Pacific countries / regions, please visit our Asia Pacific Website and contact our local distributors for the end user's cost. (The USD prices that are shown in Asia Pacific websites are TCI's catalog prices.)
Please visit each country/region's website from the following links and confirm the prices.