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1-Amidinopyrazole hydrochloride (1) reacts with primary and secondary amines to yield the corresponding guanidines.1) Moreover, the N-Boc/Ts-protected guanidine 3 can be also obtained using the corresponding N-Boc/Ts-protected derivative 2.2) It is also reported that a solid phase guanidinylation can be performed using cellulose-suported guanidine compound 4.3)


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