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An Osteogenic Small Compound (TH)

No.181(August 2019)
TH  (1)
The helioxanthin analogue (TH) (1) is a first osteogenic small compound that was reported by Ohba et al.1) In their reports, 1 not only stimulates osteoblast differentiation of osteoblast precursors, but also enhances bone regeneration in rodent bone defect models.2,3) The osteogenic effects are also observed in mouse and human pluripotent stem cells4,5) as well as human dental pulp stem cells.6) 1 is one of the most promising compound for inducing bone regeneration.
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