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Topoisomerase Inhibitor

No.177(April 2018)
Gatifloxacin Hydrate  (1)
Gatifloxacin (1) is one of the fluoroquinolone antibiotics and shows a broad spectrum of antibacterial activity against gram-positive and gram-negative bacteria.1) 1 inhibits bacterial DNA gyrase and topoisomerase IV (Table 1).2) Furthermore, 1 promotes short-term self-renewal and differentiation of human embryonic stem cells.3)

Table 1. Inhibition of type II topoisomerase by Gatifloxacin2)

This product is for research purpose only.


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