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Water-soluble Polymers with Biocompatiblility: Poly(2-oxazoline)s

Poly(2-oxazoline)s are biocompatible and non-immunogenic pseudo-polypeptide-structured polymers. ULTROXA® poly(2-methyl-2-oxazoline) (1), a highly-defined polymer with narrow molar mass distribution, is more hydrophilic than poly(ethylene glycol) (PEG).2a) ULTROXA® poly(2-propyl-2-oxazoline) (2) with a narrow molar mass distribution transitions to a hydrophobic state in water when heated.3a) 1 and 2 have been applied to surface coating,1) drug delivery systems,2) and thermoresponsive material.3)

ULTROXA® is a registered trademark of Ghent University.


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