Home > Featured Industries & Technical References > Quarterly Printed Magazine "TCIMAIL" > Back Numbers > Alkylation Reagents for Ester Synthesis

Alkylation Reagents for Ester Synthesis

O-Alkylisoureas (1) to (5) are convenient and useful esterification reagents for the direct alkylation of carboxylic acids. For example, Golding et al. have reported the esterification of 1-cyclobutenecarboxylic acid using 1, affording the corresponding methyl ester.1)
Moreover, Linclau et al. have reported the microwave-accelerated esterification of carboxylic acids using 4 and 5, affording the corresponding esters in excellent yields within several minutes.2)
For another example, the esterification reaction using 2 and 3 also has been reported as below.3)

References

The prices are subject to change without notice. Please confirm the newest price by our online catalog before placing an order.
In addition, sales products changes with areas. Please understand that a product is not available when the product details page is not displayed.