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Abiraterone Acetate
(CAS RN:154229-18-2 Product Number:A2891)


Abiraterone Acetate
Synonym 3β-17-(3-Pyridyl)androsta-5,16-dien-3-ol Acetate

General Information

Product Number A2891

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature <0°C
M.F. / M.W. C26H33NO2=391.56
CAS RN 154229-18-2
Related CAS RN
MDL Number MFCD00934213
Packaging and Container
  • Product Details
  • Safety & Regulations
  • Reference & Application


Appearance White to Light yellow to Light orange powder to crystal
Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 145.0 to 149.0 deg-C
Specific rotation [a]20/D -40.0 to -45.0 deg(C=2,EtOH)


Reaxys-RN 7314563
PubChem SID 253661226
RTECS# BV7992100


Signal Word Warning
Hazard Statements
  • H302
  • :Harmful if swallowed.
  • H361
  • :Suspected of damaging fertility or the unborn child.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P202
  • :Do not handle until all safety precautions have been read and understood.
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P301+P312+P330
  • :If swallowed: Call a poison center or doctor if you feel unwell. Rinse mouth.
  • P308+P313
  • :If exposed or concerned: Get medical advice or attention.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents and container in accordance with local, regional, national regulations (e.g. US: 40 CFR Part 261, EU:91/156/EEC, JP: Waste Disposal and Cleaning Act, etc.).


Abiraterone Acetate: A Prodrug of Abiraterone [A2868]

Abiraterone acetate (CB7630) is a prodrug of abiraterone [A2868] which is a selective inhibitor of the steroidogenic enzyme cytochrome P450 17A1 (CYP17A1) which catalyzes two key serial reactions (17α-hydroxylase hydroxylase and 17,20-lyase) in androgen and estrogen biosynthesis. Abiraterone is more potent than ketoconazole [K0045] as an inhibitor of CYP17. Abiraterone acetate is an agent used in combination with prednisone [P1276] in metastatic castration-resistant prostate cancer (mCRPC). (The product is for research purpose only.)


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