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Biapenem
(CAS RN:120410-24-4 Product Number:B5522)

Structure

Biapenem

General Information

Product Number B5522

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Purity/Analysis Method >98.0%(GC)
Storage Temperature 0-10°C
M.F. / M.W. C15H18N4O4S=350.39
CAS RN 120410-24-4
Related CAS RN
MDL Number MFCD00864863
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Specification

Purity(HPLC) min. 98.0 area%
Elemental analysis(Nitrogen) 15.20 to 16.70 %
Specific rotation [a]20/D -30.0 to 335.0 deg(C=0.5, H2O)

References

Reaxys-RN 7394875
Merck Index(14) 1197

Application

Biapenem: A Carbapenem Antibacterial Agent against Pseudomonas aeruginosa

Biapenem (LJC 10627) is a carbapenem antibacterial agent that has antibacterial and fungicidal activity against a wide range of Gram-positive and -negative bacteria, including species producing β-lactamases. Biapenem also has activity against Pseudomonas aeruginosa which isolates with broad-spectrum insusceptibility to penicillins and cephalosporins. Biapenem inhibits murein biosynthesis which is needed by bacteria to make their cell walls. In addition, biapenem is more stable than meropenem [M2279] to metabolic hydrolysis by human renal dihydropeptidase-I (DHP-I). (The product is for research purpose only.)

References

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