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5-Ethyluracil
(CAS RN:4212-49-1 Product Number:E0807)

Structure

5-Ethyluracil
Synonym 2,4-Dihydroxy-5-ethylpyrimidine

General Information

Product Number E0807

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C6H8N2O2=140.14
CAS RN 4212-49-1
Related CAS RN
MDL Number MFCD00079187
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Specification

Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %

Data of Reference

mp 303°C(lit.)
λmax 265(EtOH)(lit.)

References

Beilstein 24(5)7,226
Reaxys-RN 119494
PubChem SID 87561056

Application

beta-Stereoselective synthesis of an 2’-fluoro-5-ethylarabinouridine derivative with silylated 5-ethyluracil

Typical procedure (synthesis of 2,4-bis-O-(trimethylsilyl)-5-ethyluracil): A suspension of 5-ethyluacil (0.408 mol), hexamethyldisilazane (0.457 mol), ammonium sulfate (0.037 mol), and 1.45 L of CH3CN is stirred at reflux 3h. The solution is evaporated under reduce pressure to an oil which can be used without further treatment.

References

PubMed Literature

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