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5-Fluorouracil
(CAS RN:51-21-8 Product Number:F0151)

Structure

5-Fluorouracil
Synonym 5-FU

General Information

Product Number F0151

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Purity/Analysis Method >99.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C4H3FN2O2=130.08
CAS RN 51-21-8
Related CAS RN
MDL Number MFCD00006018
Packaging and Container
  • Product Details
  • Safety & Regulations
  • Reference & Application

Specification

Purity(HPLC) min. 99.0 area%
Purity(Neutralization titration) min. 99.0 %
Solubility in hot Water almost transparency

Data of Reference

mp 283°C(dec.)(lit.)

References

Reaxys-RN 127172
PubChem SID 87569939
Merck Index(14) 4181
RTECS# YR0350000

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H301
  • :Toxic if swallowed.
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, eye protection.
  • P301+P310+P330
  • :If swallowed: Immediately call a poison center or doctor. Rinse mouth.
  • P302+P352+P332+P313+P362+P364
  • :If on skin: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents and container in accordance with local, regional, national regulations (e.g. US: 40 CFR Part 261, EU:91/156/EEC, JP: Waste Disposal and Cleaning Act, etc.).

Transport Information

UN Number 2811
Class 6.1
Packing Group III

Application

5-Fluorouracil (5-FU): An Antitumor Antimetabolite with Activity against Numerous Types of Neoplasms

5-Fluorouracil (5-FU) is an antitumor antimetabolite with activity against numerous types of neoplasms. Further, many prodrugs of 5-FU have been developed to increased plasma and tumor 5-FU concentrations and to improve the cytotoxicity, such as capecitabine [C2878], doxifluridine [D3579], carmofur [C2663], tegaful [F0635], UFT (tegafur and uracil [U0013]) and S-1 (tegafur, gimeracil [C2243] and potassium oxonate [O0164]). (The product is for research purpose only.)

References

Reagent for gastropathy (gastric mucosal injury) model

References

Reagent for nausea or vomiting model

References

PubMed Literature

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