Home >   Products   >  Advanced Search

(CAS RN:211555-04-3 Product Number:W0013)


Synonym 2-Bromo-4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenol

General Information

Product Number W0013

* Items available from stock in Japan will be delivered in 10 business days.
* Please contact us if you need further information.
(Sales Dept Tel: +49 6196 640 53 00 E-mail: Sales-DE@TCIchemicals.com)
* To send your quote request for bulk quantities, please click on the “Request Bulk Quotation” button. Please note that for some of our products we cannot offer bulk quantities.
* TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

Purity/Analysis Method >98.0%(HPLC)
Storage Temperature <0°C
M.F. / M.W. C16H14BrN3O3=376.21
CAS RN 211555-04-3
Related CAS RN
MDL Number MFCD02179366
Packaging and Container
  • Product Details
  • Safety & Regulations


Purity(HPLC) min. 98.0 area%
Melting point 228.0 to 232.0 deg-C
Elemental analysis(Nitrogen) 10.50 to 11.50 %

Data of Reference

λmax 335(MeOH)(lit.)


Reaxys-RN 8787580


WHI-P 154: A Potent Janus-Associated Kinase 3 (JAK3) Inhibitor

WHI-P 154 is a potent Janus-associated kinase 3 (JAK3) inhibitor that displays no activity at JAK1 or JAK2. JAK3 is a cytoplasmic protein tyrosine kinase that functions in the initiation of cytokine-triggered signal transduction by catalyzing the phosphorylation of signal transduction and activators of transcription (STAT). The phosphorylated SATAs are translocated to the nucleus to activate target genes. WHI-P 154 is cytotoxic human glioblastoma cells. Recent reports have indicated that JAK3 is expressed in lymphoid cells and is involved in the signaling of T cell functions. Therefore, the development of a selective JAK3 inhibitor has been shown to have a potential benefit in the treatment of autoimmune disorders. (The product is for research purpose only.)


Page Top