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Bikinin
(CAS RN:188011-69-0 Product Number:B4826)

Structure

Bikinin
Synonym 4-[(5-Bromo-2-pyridyl)amino]-4-oxobutyric Acid

General Information

Product Number B4826

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature 0-10°C
M.F. / M.W. C9H9BrN2O3=273.09
CAS RN 188011-69-0
Related CAS RN
MDL Number MFCD00116442
Packaging and Container
  • Product Details
  • Safety & Regulations
  • Reference & Application

Specification

Purity(HPLC) min. 98.0 area%
Purity(Neutralization titration) min. 98.0 %

Data of Reference

mp 144°C(lit.)

References

Reaxys-RN 8144877
PubChem SID 354334059

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H315
  • :Causes skin irritation.
  • H319
  • :Causes serious eye irritation.
Precautionary Statements
  • P264
  • :Wash hands and face thoroughly after handling.
  • P280
  • :Wear protective gloves, eye protection.
  • P302+P352+P332+P313+P362+P364
  • :If on skin: Wash with plenty of soap and water. If skin irritation occurs: Get medical advice or attention. Take off contaminated clothing and wash it before reuse.
  • P305+P351+P338+P337+P313
  • :If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

Application

Bikinin: An ATP-Competitive GSK-3-Like BIN2 Kinase Inhibitor

Bikinin is an ATP-competitive glycogen synthase kinase 3 (GSK-3) like kinase BIN2 inhibitor. Bikinin directly binds the GSK-3-like BIN2 kinase which can modulate many more signaling components involved in brassinosteroids (BRs) which promote plant growth and developmental processes. Therefore, bikinin acts as a strong activator of BR signaling.

References

PubMed Literature

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