Home >   Products   >  Advanced Search

β-Isocupreidine
(CAS RN:253430-48-7 Product Number:I0728)

Structure

beta-Isocupreidine
Synonym (9S)-3α,9-Epoxy-10,11-dihydrocinchonan-6'-ol
Synonym β-ICD

General Information

Product Number I0728

* Please contact our distributor or us if you would like to know purchase prices in Australia that include freight cost, customs charge and other charges to the destination.
* To send your quote request for bulk quantities, please click on the "Request Bulk Quotation" button. Please note that we cannot offer bulk quantities for some products.
* TCI frequently reviews storage conditions to optimize them. Please note that the latest information on the storage temperature for the products is described on our website.

Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C19H22N2O2=310.40
CAS RN 253430-48-7
Related CAS RN
MDL Number
Packaging and Container
  • Product Details
  • Safety & Regulations
  • Reference & Application

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Specific rotation [a]20/D -10.0 to -16.0 deg(C=1, EtOH)

Data of Reference

mp 259°C(lit.)

References

Beilstein 27(4)7371
Reaxys-RN 90431
PubChem SID 87560921

Application

Useful Cinchona Alkaloid Derived Catalysts

Typical Procedure:
1 or 2 (0.1 or 0.2 mmol) is dissolved in THF (2 mL) and the solution is evaporated by rotary evaporation at room temperature. After repeating this operation three times, the amorphous residue is dried under vacuum at room temperature for 10 min. A solution of the dried 1 or 2 and aldehyde (1.0 mmol) in DMF is cooled to –55 °C, and HFIPA (1.3 mmol) is then added. After the mixture is stirred at –55 °C, the reaction is quenched by the addition of 0.1 M HCl (3 mL). The mixture is extracted with EtOAc, washed with saturated NaHCO3 and brine, dried over MgSO4, concentrated, and chromatographed on silica gel (hexane-EtOAc) to give the corresponding products.

References

PubMed Literature

Page Top