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Pomalidomide
(CAS RN:19171-19-8 Product Number:P2074)

Structure

Pomalidomide
Synonym 3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide

General Information

Product Number P2074

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Purity/Analysis Method >98.0%(HPLC)
Storage Temperature 0-10°C
M.F. / M.W. C13H11N3O4=273.25
CAS RN 19171-19-8
Related CAS RN
MDL Number MFCD12756407
Packaging and Container
  • Product Details
  • Safety & Regulations
  • Reference & Application

Specification

Purity(HPLC) min. 98.0 area%

References

Reaxys-RN 8340987
PubChem SID 253660183
Merck Index(14) 135
RTECS# NR3397905

GHS

Pictogram
Signal Word Warning
Hazard Statements
  • H361
  • :Suspected of damaging fertility or the unborn child.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P202
  • :Do not handle until all safety precautions have been read and understood.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P308+P313
  • :If exposed or concerned: Get medical advice or attention.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents and container in accordance with local, regional, national regulations (e.g. US: 40 CFR Part 261, EU:91/156/EEC, JP: Waste Disposal and Cleaning Act, etc.).

Application

A Potent Anti-Myeloma, Anti-Inflammatory and Immunomodulatory Agent, Pomalicomide

Pomalidomide (CC-4047), a thalidomide analog, is an immunomodulatory agent with numerous effects on the body's immune system, and has potent anti-myeloma and anti-inflammatory activities in vitro and in vivo. Pomalidomide inhibits the cytokines tumor necrosis factor-α (TNF-α), interleukins (IL) 1β, 6, 12, and granulocyte macrophage-colony stimulating factor (GM-CSF).

References

PubMed Literature

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