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N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium Tetrafluoroborate
(CAS RN:105832-38-0 Product Number:T2224)


N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium Tetrafluoroborate
Synonym O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium Tetrafluoroborate
Synonym TSTU

General Information

Product Number T2224

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Purity/Analysis Method >98.0%(HPLC)(N)
Storage Temperature 0-10°C
M.F. / M.W. C9H16BF4N3O3=301.05
CAS RN 105832-38-0
Related CAS RN
MDL Number
Packaging and Container
  • Product Details
  • Safety & Regulations
  • Reference & Application


Purity(HPLC) min. 98.0 area%
Purity(with Total Nitrogen) min. 98.0 %


Reaxys-RN 4345014
PubChem SID 87558325


Signal Word Danger
Hazard Statements
  • H302
  • :Harmful if swallowed.
  • H314
  • :Causes severe skin burns and eye damage.
Precautionary Statements
  • P260
  • :Do not breathe dusts or mists.
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P301+P330+P331+P310
  • :If swallowed: Rinse mouth. Do NOT induce vomiting. Immediately call a poison center or doctor.
  • P303+P361+P353+P310+P363
  • :If on skin (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower. Immediately call a poison center or doctor. Wash contaminated clothing before reuse.
  • P304+P340+P310
  • :If inhaled: Remove person to fresh air and keep comfortable for breathing. Immediately call a poison center or doctor.
  • P305+P351+P338+P310
  • :If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a poison center or doctor.
  • P405
  • :Store locked up.
  • P501
  • :Dispose of contents and container in accordance with local, regional, national regulations (e.g. US: 40 CFR Part 261, EU:91/156/EEC, JP: Waste Disposal and Cleaning Act, etc.).

Transport Information

UN Number 1759
Class 8
Packing Group III


A Condensing Agent

Experimental procedure: the compound 1 (2.0 g, 7.2 mmol) is dissolved in anhydrous acetonitrile (30 mL). The solution is cooled to -5 °C, and triethylamine (1.0 mL, 7.2 mmol) and then TSTU (2.17 g, 7.2 mmol) are added. The mixture is stirred for 1 h at -5 °C, and then a solution of 2 (1.28 g, 14.4 mmol) and NaHCO3 (1.21 g, 14.4 mmol) in water (20 mL) is added. The reaction mixture is mixed 3 h at room temperature. The solvent is evaporated in vacuo to dryness. Then water (20 mL) is added, and pH of the mixture is brought to 3. The product is extracted from water by chloroform (2 × 150 mL). The organic layer is washed by 1 mol/L HCl (2 × 50 mL) and water (50 mL), then dried with Na2SO4, filtered, and the solvent is evaporated in vacuo. The resulting oily residue is dissolved in diethylether (50 mL), and the precipitate is collected by filtration and dried to give 3 in 81% yield.


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