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Atipamezole Hydrochloride
(CAS RN:104075-48-1 Product Number:A2956)

Structure

Atipamezole Hydrochloride
Synonym 4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-imidazole Hydrochloride

General Information

Product Number A2956

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Purity/Analysis Method >98.0%(HPLC)(T)
Storage Temperature
M.F. / M.W. C14H16N2·HCl=248.75
CAS RN 104075-48-1
Related CAS RN 104054-27-5
MDL Number MFCD06407819
Packaging and Container
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  • Safety & Regulations

Specification

Purity(HPLC) min. 98.0 area%
Purity(Nonaqueous Titration) min. 98.0 %
Melting point 218.0 to 222.0 deg-C

References

Reaxys-RN 8164642
PubChem SID 354334070
Merck Index(14) 861
RTECS# NI6139000

Transport Information

HS Number 2933299090

Application

Atipamezole: An α2-Adrenoceptor Antagonist

Atipamezole hydrochloride is a potent and selective α2-adrenoceptor antagonist with an imidazole structure. In animals, it promotes the release of the neurotransmitter noradrenaline in the central as well as in the peripheral nervous systems. The α21 selectivity ratio are considerably higher than those of yohimbine hydrochloride [Y0002]. Unlike many other α2-adrenoceptor antagonists, atipamezole has negligible affinity for 5-HT1A receptors. Atipamezole hydrochloride is used for the reversal of an α2-agonist (e.g. xylazine hydrochloride [X0059]) induced sedation in animals. (The product is for research purpose only.)

References

PubMed Literature

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