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Colchicine (contains 5% Ethyl Acetate at maximum)
(CAS RN:64-86-8 Product Number:C0380)

Structure

Colchicine

General Information

Product Number C0380

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Purity/Analysis Method >97.0%(HPLC)
Storage Temperature
M.F. / M.W. C22H25NO6=399.44
CAS RN 64-86-8
Related CAS RN
MDL Number MFCD00078484
Packaging and Container
  • Product Details
  • Safety & Regulations

Specification

Purity(HPLC) min. 97.0 area%
Purity(Nonaqueous Titration) min. 95.0 %(calcd.on dried substance)
Specific rotation [a]20/D -230 to -245 deg(C=1, EtOH)
Drying loss max. 5.0 %

References

Beilstein 14(3)693
Reaxys-RN 2228813
PubChem SID 87565511
Merck Index(14) 2471
RTECS# GH0700000
EC Number 200-598-5

GHS

Pictogram
Signal Word Danger
Hazard Statements
  • H300
  • :Fatal if swallowed.
  • H340
  • :May cause genetic defects.
Precautionary Statements
  • P201
  • :Obtain special instructions before use.
  • P264
  • :Wash hands and face thoroughly after handling.
  • P270
  • :Do not eat, drink or smoke when using this product.
  • P280
  • :Wear protective gloves, protective clothing, face protection.
  • P301+P310+P330
  • :IF SWALLOWED: Immediately call a POISON CENTER or doctor. Rinse mouth.
  • P308+P313
  • :IF exposed or concerned: Get medical advice or attention.

Transport Information

UN Number 1544
Class 6.1
Packing Group III
HS Number 2939790090

Application

Colchicine: An Antimitotic Alkaloid

Colchicine is an alkaloid, extracted from plants of the genus Colchicum. Colchicine inhibits β-tubulin polymerization into microtubules by binding to tubulin. Thus, colchicine is an antimitotic agent with a great pharmaceutical potential as an antitumor agent. Colchicine also inhibits neutrophil motility and activity, leading to a net anti-inflammatory effect. (The product is for research purpose only.)

References

PubMed Literature

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